Two cases of proximal subungual onychomycosis caused by Trichophyton rubrum in HIV-negative patients during treatment with TNF-α inhibitors combined with methotrexate

Pernille Lindsø Andersen; Mattias Arvid Simon Henning; Gregor B.E. Jemec; Maiken Cavling Arendrup; Ditte Marie L. Saunte

Two cases of proximal subungual onychomycosis caused by Trichophyton rubrum in HIV-negative patients during treatment with TNF-α inhibitors combined with methotrexate

Pernille Lindsø Andersen
, Mattias Arvid Simon Henning
, Gregor B.E. Jemec
, Maiken Cavling Arendrup
, Ditte Marie L. Saunte^*

^*Corresponding author for this work

Dermatology

Research output: Contribution to journal › Article › Research › peer-review

Abstract

Proximal subungual onychomycosis (PSO) is a rare subtype of onychomycosis with a clinical presentation characterized by proximal leukonychia in the lunular area of the nail. PSO is associated with immunosuppression and regarded a sign of Human Immunodeficiency Virus (HIV) infection when caused by Trichophyton (T.) rubrum. We present two cases of PSO caused by T. rubrum developed during treatment with TNF-α inhibitors combined with methotrexate (MTX).

Original language	English
Pages (from-to)	304-306
Number of pages	3
Journal	Acta Dermatovenerologica Croatica
Volume	26
Issue number	4
Publication status	Published - 1 Jan 2018

Keywords

Immunosuppresive agents
Methotrexate
Nail diseases
Onychomycosis
Psoriasis
Tumor necrosis factor-alpha

Cite this

@article{e0f3e06f1a554afcb4ff186d3f5c92bb,

title = "Two cases of proximal subungual onychomycosis caused by Trichophyton rubrum in HIV-negative patients during treatment with TNF-α inhibitors combined with methotrexate",

abstract = "Proximal subungual onychomycosis (PSO) is a rare subtype of onychomycosis with a clinical presentation characterized by proximal leukonychia in the lunular area of the nail. PSO is associated with immunosuppression and regarded a sign of Human Immunodeficiency Virus (HIV) infection when caused by Trichophyton (T.) rubrum. We present two cases of PSO caused by T. rubrum developed during treatment with TNF-α inhibitors combined with methotrexate (MTX).",

keywords = "Immunosuppresive agents, Methotrexate, Nail diseases, Onychomycosis, Psoriasis, Tumor necrosis factor-alpha",

author = "Andersen, \{Pernille Linds{\o}\} and Henning, \{Mattias Arvid Simon\} and Jemec, \{Gregor B.E.\} and Arendrup, \{Maiken Cavling\} and Saunte, \{Ditte Marie L.\}",

year = "2018",

month = jan,

day = "1",

language = "English",

volume = "26",

pages = "304--306",

journal = "Acta Dermatovenerologica Croatica",

issn = "1330-027X",

publisher = "Croatian Dermatovenerological Society",

number = "4",

}

Two cases of proximal subungual onychomycosis caused by Trichophyton rubrum in HIV-negative patients during treatment with TNF-α inhibitors combined with methotrexate. / Andersen, Pernille Lindsø; Henning, Mattias Arvid Simon; Jemec, Gregor B.E. et al.
In: Acta Dermatovenerologica Croatica, Vol. 26, No. 4, 01.01.2018, p. 304-306.

Research output: Contribution to journal › Article › Research › peer-review

TY - JOUR

T1 - Two cases of proximal subungual onychomycosis caused by Trichophyton rubrum in HIV-negative patients during treatment with TNF-α inhibitors combined with methotrexate

AU - Andersen, Pernille Lindsø

AU - Henning, Mattias Arvid Simon

AU - Jemec, Gregor B.E.

AU - Arendrup, Maiken Cavling

AU - Saunte, Ditte Marie L.

PY - 2018/1/1

Y1 - 2018/1/1

N2 - Proximal subungual onychomycosis (PSO) is a rare subtype of onychomycosis with a clinical presentation characterized by proximal leukonychia in the lunular area of the nail. PSO is associated with immunosuppression and regarded a sign of Human Immunodeficiency Virus (HIV) infection when caused by Trichophyton (T.) rubrum. We present two cases of PSO caused by T. rubrum developed during treatment with TNF-α inhibitors combined with methotrexate (MTX).

AB - Proximal subungual onychomycosis (PSO) is a rare subtype of onychomycosis with a clinical presentation characterized by proximal leukonychia in the lunular area of the nail. PSO is associated with immunosuppression and regarded a sign of Human Immunodeficiency Virus (HIV) infection when caused by Trichophyton (T.) rubrum. We present two cases of PSO caused by T. rubrum developed during treatment with TNF-α inhibitors combined with methotrexate (MTX).

KW - Immunosuppresive agents

KW - Methotrexate

KW - Nail diseases

KW - Onychomycosis

KW - Psoriasis

KW - Tumor necrosis factor-alpha

UR - https://www.scopus.com/pages/publications/85060205978

M3 - Article

C2 - 30665479

AN - SCOPUS:85060205978

SN - 1330-027X

VL - 26

SP - 304

EP - 306

JO - Acta Dermatovenerologica Croatica

JF - Acta Dermatovenerologica Croatica

IS - 4

ER -

Two cases of proximal subungual onychomycosis caused by Trichophyton rubrum in HIV-negative patients during treatment with TNF-α inhibitors combined with methotrexate

Abstract

Keywords

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