The impact of ultraviolet therapy on stratum corneum ceramides and barrier function

Jakob Mutanu Jungersted; Julie K. Høgh; Lars I. Hellgren; Gregor B.E. Jemec; Tove Agner

doi:10.1111/j.1600-0781.2011.00618.x

The impact of ultraviolet therapy on stratum corneum ceramides and barrier function

Jakob Mutanu Jungersted^*
, Julie K. Høgh
, Lars I. Hellgren
, Gregor B.E. Jemec
, Tove Agner

^*Corresponding author for this work

Dermatology

Research output: Contribution to journal › Article › Research › peer-review

Abstract

The ceramide profile as well as the barrier function is known to be deteriorated in atopic eczema and psoriasis, and ultraviolet (UV) light is known to improve the barrier function. The impact of UV light on ceramides, however, is not clarified. The aim of this study was to examine the effect of UV therapy in dermatological patients on ceramides and skin barrier function. We found that UV light treatment does not change the ratio of important stratum corneum lipids, but we confirm earlier findings of decreased susceptibility to irritants after UV- therapy.

Original language	English
Pages (from-to)	331-333
Number of pages	3
Journal	Photodermatology Photoimmunology and Photomedicine
Volume	27
Issue number	6
DOIs	https://doi.org/10.1111/j.1600-0781.2011.00618.x
Publication status	Published - 1 Dec 2011

Keywords

Ceramides
Skin barrier measurements
UV light therapy

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10.1111/j.1600-0781.2011.00618.x

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title = "The impact of ultraviolet therapy on stratum corneum ceramides and barrier function",

abstract = "The ceramide profile as well as the barrier function is known to be deteriorated in atopic eczema and psoriasis, and ultraviolet (UV) light is known to improve the barrier function. The impact of UV light on ceramides, however, is not clarified. The aim of this study was to examine the effect of UV therapy in dermatological patients on ceramides and skin barrier function. We found that UV light treatment does not change the ratio of important stratum corneum lipids, but we confirm earlier findings of decreased susceptibility to irritants after UV- therapy.",

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AU - Jungersted, Jakob Mutanu

AU - Høgh, Julie K.

AU - Hellgren, Lars I.

AU - Jemec, Gregor B.E.

AU - Agner, Tove

PY - 2011/12/1

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N2 - The ceramide profile as well as the barrier function is known to be deteriorated in atopic eczema and psoriasis, and ultraviolet (UV) light is known to improve the barrier function. The impact of UV light on ceramides, however, is not clarified. The aim of this study was to examine the effect of UV therapy in dermatological patients on ceramides and skin barrier function. We found that UV light treatment does not change the ratio of important stratum corneum lipids, but we confirm earlier findings of decreased susceptibility to irritants after UV- therapy.

AB - The ceramide profile as well as the barrier function is known to be deteriorated in atopic eczema and psoriasis, and ultraviolet (UV) light is known to improve the barrier function. The impact of UV light on ceramides, however, is not clarified. The aim of this study was to examine the effect of UV therapy in dermatological patients on ceramides and skin barrier function. We found that UV light treatment does not change the ratio of important stratum corneum lipids, but we confirm earlier findings of decreased susceptibility to irritants after UV- therapy.

KW - Ceramides

KW - Skin barrier measurements

KW - UV light therapy

UR - https://www.scopus.com/pages/publications/81355151457

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JO - Photodermatology Photoimmunology and Photomedicine

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IS - 6

ER -

The impact of ultraviolet therapy on stratum corneum ceramides and barrier function

Abstract

Keywords

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