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Seminar in Epileptology: Normal awake and sleep patterns, interictal abnormalities, and ictal patterns on scalp EEG

  • Juan Luis Alcala-Zermeno*
  • , Roohi Katyal
  • , Birgit Frauscher
  • , Donald Schomer
  • , Michael R Sperling
  • , Roy Strowd
  • , William O Tatum
  • , Elaine Wirrell
  • , Sándor Beniczky
  • , Fábio A Nascimento
  • *Corresponding author for this work

Research output: Contribution to journalReviewResearchpeer-review

Abstract

The accurate interpretation of scalp EEG remains an instrumental diagnostic component of epilepsy care. Knowledge of what constitutes normal EEG findings, non-epileptiform abnormalities, and epileptiform patterns-both ictal and interictal-is essential for appropriate patient management. The International League Against Epilepsy (ILAE) has developed an educational curriculum containing learning objectives necessary to accurately diagnose and manage people with epilepsy. In this Seminar in Epileptology, we address the learning objectives related to assessment and interpretation of EEG background activity, normal sleep patterns, provocation methods, interictal abnormalities, and ictal patterns, as well as a brief discussion on relevant advances in scalp EEG analysis and future perspectives on this topic.

Original languageEnglish
Pages (from-to)803-866
Number of pages64
JournalEpileptic Disorders
Volume27
Issue number5
Early online date9 Aug 2025
DOIs
Publication statusPublished - Oct 2025

Keywords

  • Electroencephalography/methods
  • Epilepsy/physiopathology
  • Humans
  • Scalp/physiopathology
  • Sleep/physiology
  • Wakefulness/physiology

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