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Regulation of bone mass in endocrine diseases including diabetes

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Abstract

Hormonal regulation plays a key role in determining bone mass in humans. Both skeletal growth and bone loss in health and disease is critically controlled by endocrine factors and low bone mass is a feature of both excess and deficiency of a broad range of hormones. This article explores the impact of diabetes and thyroid, parathyroid, sex steroid and growth hormone disorders on bone mass and fracture risk. Evidence for current management strategies is provided along with suggested practice points and gaps in knowledge for future research.

Original languageEnglish
Article number101614
JournalBest Practice and Research in Clinical Endocrinology and Metabolism
Volume36
Issue number2
Early online date21 Jan 2022
DOIs
Publication statusPublished - Mar 2022

Keywords

  • thyrotoxicosis
  • primary hyperparathyroidism
  • type 1 and type 2 diabetes mellitus
  • Cushing's syndrome
  • growth hormone
  • low bone mass

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