Abstract
The use of magnetic resonance (MR) velocity mapping in the quantification of aortic valvular blood flow was examined in 10 patients with angiographically verified aortic regurgitation. MR velocity mapping succeeded in identifying and quantifying the regurgitation in all patients, and the regurgitant volume determined with MR velocity mapping agreed well with the grade obtained by aortic root angiography (p < 0.02). The accuracy in quantification of the aortic valvular flow rate was demonstrated by a significant correlation between the stroke volume (ml) measured by MR velocity mapping and calculated from MR imaging of the left ventricular end-diastolic and end-systolic volumes in eight patients (Y = 0.89 · X + 11, r = 0.97, p < 0.001). This finding was confirmed by a good agreement between the net cardiac output (L/min) quantified with MR velocity mapping and simultaneous 125I-indicator dilution measurement in all subjects (Y = 0.89 · X + 0.08, r = 0.82, p < 0.01). In conclusion, MR velocity mapping may be used as a noninvasive tool in the quantification of aortic regurgitation.
| Original language | English |
|---|---|
| Pages (from-to) | 1081-1090 |
| Number of pages | 10 |
| Journal | American heart journal |
| Volume | 125 |
| Issue number | 4 |
| DOIs | |
| Publication status | Published - Apr 1993 |
Funding
“From the Danish Research Centre of Magnetic Resonance, Hvidovre Hospital, University of Copenhagen, bthe Department of Cardiology, Gentofte Hospital, University of Copenhagen, and Yhe Department of Radiation Physics, Lund University Hospital. Supported by grants from the Danish Heart Foundation and the Danish Health Research Counsel (grant 12-96356) and by The Scandinavian Flow Group. Received for publication May 28, 1992; accepted Oct. 15, 1992. Reprint requests: Lars S$ndergaard, MD, Danish Research Centre of Magnetic Resonance, Hvidovre University Hospital, Kettegard Alle 30, DK-2650 Hvidovre, Denmark. Copyright 0 1993 by Mosby-Year Book, Inc. 0002-8703/93/$1.00 + .lO 4/14/43801