Platformsforsøg

Anders Perner; Maj-Brit N Kjær; Hans-Christian Thorsen-Meyer; Benjamin Skov Kaas-Hansen; Marie Warrer Munch; M. O. Collet; Camilla RL Bruun; Aksel Karl Georg Jensen; Theis Lange; Trine Albertsen; Claus Duedal Pedersen; Lone Musaeus Poulsen; Ole Mathiesen; Anne Craveiro Brøchner; Thomas Strøm; Lars W Andersen; Steffen Christensen; Bodil S Rasmussen; Olav L Schjørring; Mathias Maagaard; Morten Hylander Møller; Anders Granholm

Platformsforsøg

Translated title of the contribution: Platform trials

Anders Perner
, Maj-Brit N Kjær
, Hans-Christian Thorsen-Meyer
, Benjamin Skov Kaas-Hansen
, Marie Warrer Munch
, M. O. Collet
, Camilla RL Bruun
, Aksel Karl Georg Jensen
, Theis Lange
, Trine Albertsen
, Claus Duedal Pedersen
, Lone Musaeus Poulsen
, Ole Mathiesen
, Anne Craveiro Brøchner
, Thomas Strøm
, Lars W Andersen
, Steffen Christensen
, Bodil S Rasmussen
, Olav L Schjørring
, Mathias Maagaard

Morten Hylander Møller, Anders Granholm

Anaesthesiology

Research output: Contribution to journal › Article › Research › peer-review

Abstract

Platform trials focus on the perpetual testing of many interventions in a disease or a setting. These trials have lasting organizational, administrative, data, analytic, and operational frameworks making them highly efficient. The use of adaptation often increases the probabilities of allocating participants to better interventions and obtaining conclusive results. The COVID-19 pandemic showed the potential of platform trials as a fast and valid way to improved treatments. This review gives an overview of key concepts and elements using the Intensive Care Platform Trial (INCEPT) as an example.

Translated title of the contribution	Platform trials
Original language	Danish
Article number	V04230237
Number of pages	10
Journal	Ugeskrift for Laeger
Volume	185
Issue number	41
Publication status	Published - 9 Oct 2023

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https://ugeskriftet.dk/videnskab/platformsforsog

Cite this

Perner, A., Kjær, M.-B. N., Thorsen-Meyer, H.-C., Kaas-Hansen, B. S., Munch, M. W., Collet, M. O., Bruun, C. RL., Jensen, A. K. G., Lange, T., Albertsen, T., Duedal Pedersen, C., Poulsen, L. M., Mathiesen, O., Brøchner, A. C., Strøm, T., Andersen, L. W., Christensen, S., S Rasmussen, B., L Schjørring, O., ... Granholm, A. (2023). Platformsforsøg. Ugeskrift for Laeger, 185(41), Article V04230237. https://ugeskriftet.dk/videnskab/platformsforsog

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title = "Platformsfors{\o}g",

abstract = "Platform trials focus on the perpetual testing of many interventions in a disease or a setting. These trials have lasting organizational, administrative, data, analytic, and operational frameworks making them highly efficient. The use of adaptation often increases the probabilities of allocating participants to better interventions and obtaining conclusive results. The COVID-19 pandemic showed the potential of platform trials as a fast and valid way to improved treatments. This review gives an overview of key concepts and elements using the Intensive Care Platform Trial (INCEPT) as an example.",

keywords = "COVID-19/epidemiology, Humans, Pandemics",

author = "Anders Perner and Kj{\ae}r, \{Maj-Brit N\} and Hans-Christian Thorsen-Meyer and Kaas-Hansen, \{Benjamin Skov\} and Munch, \{Marie Warrer\} and Collet, \{M. O.\} and Bruun, \{Camilla RL\} and Jensen, \{Aksel Karl Georg\} and Theis Lange and Trine Albertsen and \{Duedal Pedersen\}, Claus and Poulsen, \{Lone Musaeus\} and Ole Mathiesen and Br{\o}chner, \{Anne Craveiro\} and Thomas Str{\o}m and Andersen, \{Lars W\} and Steffen Christensen and \{S Rasmussen\}, Bodil and \{L Schj{\o}rring\}, Olav and Mathias Maagaard and \{Hylander M{\o}ller\}, Morten and Anders Granholm",

note = "Published under Open Access CC-BY-NC-BD 4.0. https://creativecommons.org/licenses/by-nc-nd/4.0/.",

year = "2023",

month = oct,

day = "9",

language = "Dansk",

volume = "185",

journal = "Ugeskrift for Laeger",

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Perner, A, Kjær, M-BN, Thorsen-Meyer, H-C, Kaas-Hansen, BS, Munch, MW, Collet, MO, Bruun, CRL, Jensen, AKG, Lange, T, Albertsen, T, Duedal Pedersen, C, Poulsen, LM , Mathiesen, O, Brøchner, AC, Strøm, T, Andersen, LW, Christensen, S, S Rasmussen, B, L Schjørring, O, Maagaard, M, Hylander Møller, M & Granholm, A 2023, 'Platformsforsøg', Ugeskrift for Laeger, vol. 185, no. 41, V04230237. <https://ugeskriftet.dk/videnskab/platformsforsog>

TY - JOUR

T1 - Platformsforsøg

AU - Perner, Anders

AU - Kjær, Maj-Brit N

AU - Thorsen-Meyer, Hans-Christian

AU - Kaas-Hansen, Benjamin Skov

AU - Munch, Marie Warrer

AU - Collet, M. O.

AU - Bruun, Camilla RL

AU - Jensen, Aksel Karl Georg

AU - Lange, Theis

AU - Albertsen, Trine

AU - Duedal Pedersen, Claus

AU - Poulsen, Lone Musaeus

AU - Mathiesen, Ole

AU - Brøchner, Anne Craveiro

AU - Strøm, Thomas

AU - Andersen, Lars W

AU - Christensen, Steffen

AU - S Rasmussen, Bodil

AU - L Schjørring, Olav

AU - Maagaard, Mathias

AU - Hylander Møller, Morten

AU - Granholm, Anders

N1 - Published under Open Access CC-BY-NC-BD 4.0. https://creativecommons.org/licenses/by-nc-nd/4.0/.

PY - 2023/10/9

Y1 - 2023/10/9

N2 - Platform trials focus on the perpetual testing of many interventions in a disease or a setting. These trials have lasting organizational, administrative, data, analytic, and operational frameworks making them highly efficient. The use of adaptation often increases the probabilities of allocating participants to better interventions and obtaining conclusive results. The COVID-19 pandemic showed the potential of platform trials as a fast and valid way to improved treatments. This review gives an overview of key concepts and elements using the Intensive Care Platform Trial (INCEPT) as an example.

AB - Platform trials focus on the perpetual testing of many interventions in a disease or a setting. These trials have lasting organizational, administrative, data, analytic, and operational frameworks making them highly efficient. The use of adaptation often increases the probabilities of allocating participants to better interventions and obtaining conclusive results. The COVID-19 pandemic showed the potential of platform trials as a fast and valid way to improved treatments. This review gives an overview of key concepts and elements using the Intensive Care Platform Trial (INCEPT) as an example.

KW - COVID-19/epidemiology

KW - Humans

KW - Pandemics

M3 - Artikel

C2 - 37873986

SN - 0041-5782

VL - 185

JO - Ugeskrift for Laeger

JF - Ugeskrift for Laeger

IS - 41

M1 - V04230237

ER -

Platformsforsøg

Abstract

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