Osteodystrofi ved kronisk leversygdom

Pia Eiken; Atheer Adel Al-Omran; Frank Vinholt Schiødt

doi:10.61409/V12230769

Osteodystrofi ved kronisk leversygdom

Translated title of the contribution: Osteodystrophy in chronic liver disease

Pia Eiken^*
, Atheer Adel Al-Omran
, Frank Vinholt Schiødt

^*Corresponding author for this work

Medicine (NSR)

Research output: Contribution to journal › Review › Research › peer-review

Abstract

Hepatic osteodystrophy is defined as a metabolic bone disease that may occur in individuals with chronic liver disease (CLD). Hepatic osteodystrophy commonly manifests with osteoporosis and fragility fractures. This review finds that patients older than 50 years with CLD should be screened for possible osteoporosis earlier if they experience fragility fractures. Treatment includes calcium, vitamin D, and lifestyle interventions. Bisphosphonates, such as alendronate, and denosumab increase bone mineral density in CLD patients.

Translated title of the contribution	Osteodystrophy in chronic liver disease
Original language	Danish
Article number	V12230769
Journal	Ugeskrift for laeger
Volume	188
DOIs	https://doi.org/10.61409/V12230769
Publication status	Published, E-pub ahead of print - 8 Jun 2026

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10.61409/V12230769

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title = "Osteodystrofi ved kronisk leversygdom",

abstract = "Hepatic osteodystrophy is defined as a metabolic bone disease that may occur in individuals with chronic liver disease (CLD). Hepatic osteodystrophy commonly manifests with osteoporosis and fragility fractures. This review finds that patients older than 50 years with CLD should be screened for possible osteoporosis earlier if they experience fragility fractures. Treatment includes calcium, vitamin D, and lifestyle interventions. Bisphosphonates, such as alendronate, and denosumab increase bone mineral density in CLD patients.",

keywords = "Humans, Liver Diseases/complications, Osteoporosis/etiology, Chronic Disease, Bone Diseases, Metabolic/etiology, Bone Density Conservation Agents/therapeutic use, Vitamin D/therapeutic use, Bone Density/drug effects",

author = "Pia Eiken and Al-Omran, \{Atheer Adel\} and Schi{\o}dt, \{Frank Vinholt\}",

note = "Published under Open Access CC-BY-NC-ND 4.0. https://creativecommons.org/licenses/by-nc-nd/4.0/.",

year = "2026",

month = jun,

day = "8",

doi = "10.61409/V12230769",

language = "Dansk",

volume = "188",

journal = "Ugeskrift for laeger",

issn = "0041-5782",

publisher = "Almindelige Danske Laegeforening",

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TY - JOUR

T1 - Osteodystrofi ved kronisk leversygdom

AU - Eiken, Pia

AU - Al-Omran, Atheer Adel

AU - Schiødt, Frank Vinholt

N1 - Published under Open Access CC-BY-NC-ND 4.0. https://creativecommons.org/licenses/by-nc-nd/4.0/.

PY - 2026/6/8

Y1 - 2026/6/8

N2 - Hepatic osteodystrophy is defined as a metabolic bone disease that may occur in individuals with chronic liver disease (CLD). Hepatic osteodystrophy commonly manifests with osteoporosis and fragility fractures. This review finds that patients older than 50 years with CLD should be screened for possible osteoporosis earlier if they experience fragility fractures. Treatment includes calcium, vitamin D, and lifestyle interventions. Bisphosphonates, such as alendronate, and denosumab increase bone mineral density in CLD patients.

AB - Hepatic osteodystrophy is defined as a metabolic bone disease that may occur in individuals with chronic liver disease (CLD). Hepatic osteodystrophy commonly manifests with osteoporosis and fragility fractures. This review finds that patients older than 50 years with CLD should be screened for possible osteoporosis earlier if they experience fragility fractures. Treatment includes calcium, vitamin D, and lifestyle interventions. Bisphosphonates, such as alendronate, and denosumab increase bone mineral density in CLD patients.

KW - Humans

KW - Liver Diseases/complications

KW - Osteoporosis/etiology

KW - Chronic Disease

KW - Bone Diseases, Metabolic/etiology

KW - Bone Density Conservation Agents/therapeutic use

KW - Vitamin D/therapeutic use

KW - Bone Density/drug effects

U2 - 10.61409/V12230769

DO - 10.61409/V12230769

M3 - Review

C2 - 42273844

SN - 0041-5782

VL - 188

JO - Ugeskrift for laeger

JF - Ugeskrift for laeger

M1 - V12230769

ER -

Osteodystrofi ved kronisk leversygdom

Abstract

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