In vivo measurements of the t1 relaxation processes in the bone marrow in patients with myelodysplastic syndrome: A magnetic resonance imaging study

K. E. Jensen; H. Nielsen; C. Thomsen; P. G. Sørensen; H. Karle; P. Christoffersen; O. Henriksen

doi:10.1177/028418518903000406

In vivo measurements of the t1 relaxation processes in the bone marrow in patients with myelodysplastic syndrome: A magnetic resonance imaging study

K. E. Jensen^*
, H. Nielsen
, C. Thomsen
, P. G. Sørensen
, H. Karle
, P. Christoffersen
, O. Henriksen

^*Corresponding author for this work

Research output: Contribution to journal › Article › Research › peer-review

Abstract

Nine patients with myelodysplastic syndrome (MDS) were examined with magnetic resonance imaging and in vivo T1 relaxation time measurements of the vertebral bone marrow in a 1.5 tesla whole body scanner. Two patients underwent transformation to acute myeloid leukemia and were evaluated at follow-up examinations. At the time of diagnosis the T1 relaxation times of the vertebral bone marrow were significantly prolonged compared with normal values. The T1 relaxation times of the vertebral bone marrow in patients with MDS showed significantly lower values compared with patients with acute leukemia and did not differ from patients with polycythemia vera.

Original language	English
Pages (from-to)	365-368
Number of pages	4
Journal	Acta Radiologica
Volume	30
Issue number	4
DOIs	https://doi.org/10.1177/028418518903000406
Publication status	Published - Jul 1989

Keywords

bone marrow
in vivo tissue characterization
magnetic resonance imaging
Myelodysplastic syndrome

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title = "In vivo measurements of the t1 relaxation processes in the bone marrow in patients with myelodysplastic syndrome: A magnetic resonance imaging study",

abstract = "Nine patients with myelodysplastic syndrome (MDS) were examined with magnetic resonance imaging and in vivo T1 relaxation time measurements of the vertebral bone marrow in a 1.5 tesla whole body scanner. Two patients underwent transformation to acute myeloid leukemia and were evaluated at follow-up examinations. At the time of diagnosis the T1 relaxation times of the vertebral bone marrow were significantly prolonged compared with normal values. The T1 relaxation times of the vertebral bone marrow in patients with MDS showed significantly lower values compared with patients with acute leukemia and did not differ from patients with polycythemia vera.",

keywords = "bone marrow, in vivo tissue characterization, magnetic resonance imaging, Myelodysplastic syndrome",

author = "Jensen, \{K. E.\} and H. Nielsen and C. Thomsen and S{\o}rensen, \{P. G.\} and H. Karle and P. Christoffersen and O. Henriksen",

year = "1989",

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T1 - In vivo measurements of the t1 relaxation processes in the bone marrow in patients with myelodysplastic syndrome

T2 - A magnetic resonance imaging study

AU - Jensen, K. E.

AU - Nielsen, H.

AU - Thomsen, C.

AU - Sørensen, P. G.

AU - Karle, H.

AU - Christoffersen, P.

AU - Henriksen, O.

PY - 1989/7

Y1 - 1989/7

N2 - Nine patients with myelodysplastic syndrome (MDS) were examined with magnetic resonance imaging and in vivo T1 relaxation time measurements of the vertebral bone marrow in a 1.5 tesla whole body scanner. Two patients underwent transformation to acute myeloid leukemia and were evaluated at follow-up examinations. At the time of diagnosis the T1 relaxation times of the vertebral bone marrow were significantly prolonged compared with normal values. The T1 relaxation times of the vertebral bone marrow in patients with MDS showed significantly lower values compared with patients with acute leukemia and did not differ from patients with polycythemia vera.

AB - Nine patients with myelodysplastic syndrome (MDS) were examined with magnetic resonance imaging and in vivo T1 relaxation time measurements of the vertebral bone marrow in a 1.5 tesla whole body scanner. Two patients underwent transformation to acute myeloid leukemia and were evaluated at follow-up examinations. At the time of diagnosis the T1 relaxation times of the vertebral bone marrow were significantly prolonged compared with normal values. The T1 relaxation times of the vertebral bone marrow in patients with MDS showed significantly lower values compared with patients with acute leukemia and did not differ from patients with polycythemia vera.

KW - bone marrow

KW - in vivo tissue characterization

KW - magnetic resonance imaging

KW - Myelodysplastic syndrome

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AN - SCOPUS:84970305463

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JO - Acta Radiologica

JF - Acta Radiologica

IS - 4

ER -

In vivo measurements of the t1 relaxation processes in the bone marrow in patients with myelodysplastic syndrome: A magnetic resonance imaging study

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Keywords

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