Hidradenitis Suppurativa Prevalence in Indonesia: A Cross-Sectional Multicenter Study and Validation of a Screening Questionnaire

Shinta Trilaksmi Dewi; Nyoman Suryawati; Niken Indrastuti; Dorra Bouazzi; Cecilia E Medianfar; Robin Christensen; Gregor B E Jemec; Nisha S Chandran; Miranti Pangastuti; Aryani Adji; Gardenia Akhyar; Nopriyati Nopriyati; Cut Putri Hazlianda; Sri Awalia Febriana

doi:10.1159/000539705

Hidradenitis Suppurativa Prevalence in Indonesia: A Cross-Sectional Multicenter Study and Validation of a Screening Questionnaire

Shinta Trilaksmi Dewi
, Nyoman Suryawati
, Niken Indrastuti
, Dorra Bouazzi
, Cecilia E Medianfar
, Robin Christensen
, Gregor B E Jemec
, Nisha S Chandran
, Miranti Pangastuti
, Aryani Adji
, Gardenia Akhyar
, Nopriyati Nopriyati
, Cut Putri Hazlianda
, Sri Awalia Febriana^*

^*Corresponding author for this work

Dermatology

Research output: Contribution to journal › Article › Research › peer-review

Abstract

UNLABELLED: <p>Introduction: Studies on the prevalence of hidradenitis suppurative (HS) in Southeast Asia are scarce, and no studies have been conducted in Indonesia. This study aimed to calculate the prevalence of HS in Indonesia and validate this questionnaire in our population as part of the Global Hidradenitis Suppurativa Atlas (GHiSA) initiative.

METHODS: This multicenter cross-sectional study was conducted at 7 teaching hospitals in western and central Indonesia from December 2022 to June 2023. A total of 3,237 healthy adults accompanying patients in the outpatient clinics consented to participate. Physicians or nurses delivered the validated screening questionnaire, and photos of the axilla and groin were taken from screen-positive individuals and 10% of the screen-negative individuals. The dermatologist examined the clinical photos to confirm the diagnosis of HS.

RESULTS: The prevalence of HS in our study population was 0.43% (14/3,237; with 95% confidence interval [CI]: 0.26%-0.72%), and there was no significant difference in gender, age, body mass index (BMI), and smoking habit between the HS and non-HS groups. In the HS group, males and females were equally affected, with the median age being 29 years with interquartile range (IQR: 24.8-38.5), median BMI of 23.0 (IQR: 21.1-26.4), and 28.6% being smokers. The screening questionnaire showed a sensitivity of 0.43 (6/14; 95% CI: 0.18-0.17), specificity of 0.94 (362/386; 95% CI: 0.91-0.96), positive predictive value of 0.20 (6/30; 95% CI: 0.08-0.39), and negative predictive value of 0.98 (362/370; 95% CI: 0.96-0.99).

CONCLUSION: The prevalence of HS in Indonesia is 0.43%, slightly lower than those reported in other Southeast Asian countries. Age, gender, BMI, and smoking habits were not risk factors for HS in our population. The questionnaire is moderately accurate for screening HS but remains valuable in detecting around 50% of undiagnosed cases. </p>.

Original language	English
Pages (from-to)	57-62
Number of pages	6
Journal	Dermatology
Volume	241
Issue number	Suppl. 1
Early online date	7 Jul 2025
DOIs	https://doi.org/10.1159/000539705
Publication status	Published - 2025

Keywords

Hidradenitis suppurativa
Indonesia
Multicenter
Prevalence
Questionnaire
Cross-Sectional Studies
Humans
Middle Aged
Hidradenitis Suppurativa/epidemiology
Indonesia/epidemiology
Male
Young Adult
Female
Adult
Surveys and Questionnaires
Mass Screening/methods

Access to Document

10.1159/000539705Licence: CC BY-NC

Cite this

Dewi, S. T., Suryawati, N., Indrastuti, N., Bouazzi, D., Medianfar, C. E., Christensen, R., Jemec, G. B. E., Chandran, N. S., Pangastuti, M., Adji, A., Akhyar, G., Nopriyati, N., Hazlianda, C. P., & Febriana, S. A. (2025). Hidradenitis Suppurativa Prevalence in Indonesia: A Cross-Sectional Multicenter Study and Validation of a Screening Questionnaire. Dermatology, 241(Suppl. 1), 57-62. https://doi.org/10.1159/000539705

@article{c656fce55c6b4ea0b8432a11b91d584c,

title = "Hidradenitis Suppurativa Prevalence in Indonesia: A Cross-Sectional Multicenter Study and Validation of a Screening Questionnaire",

abstract = "UNLABELLED: Introduction: Studies on the prevalence of hidradenitis suppurative (HS) in Southeast Asia are scarce, and no studies have been conducted in Indonesia. This study aimed to calculate the prevalence of HS in Indonesia and validate this questionnaire in our population as part of the Global Hidradenitis Suppurativa Atlas (GHiSA) initiative.METHODS: This multicenter cross-sectional study was conducted at 7 teaching hospitals in western and central Indonesia from December 2022 to June 2023. A total of 3,237 healthy adults accompanying patients in the outpatient clinics consented to participate. Physicians or nurses delivered the validated screening questionnaire, and photos of the axilla and groin were taken from screen-positive individuals and 10\% of the screen-negative individuals. The dermatologist examined the clinical photos to confirm the diagnosis of HS.RESULTS: The prevalence of HS in our study population was 0.43\% (14/3,237; with 95\% confidence interval [CI]: 0.26\%-0.72\%), and there was no significant difference in gender, age, body mass index (BMI), and smoking habit between the HS and non-HS groups. In the HS group, males and females were equally affected, with the median age being 29 years with interquartile range (IQR: 24.8-38.5), median BMI of 23.0 (IQR: 21.1-26.4), and 28.6\% being smokers. The screening questionnaire showed a sensitivity of 0.43 (6/14; 95\% CI: 0.18-0.17), specificity of 0.94 (362/386; 95\% CI: 0.91-0.96), positive predictive value of 0.20 (6/30; 95\% CI: 0.08-0.39), and negative predictive value of 0.98 (362/370; 95\% CI: 0.96-0.99).CONCLUSION: The prevalence of HS in Indonesia is 0.43\%, slightly lower than those reported in other Southeast Asian countries. Age, gender, BMI, and smoking habits were not risk factors for HS in our population. The questionnaire is moderately accurate for screening HS but remains valuable in detecting around 50\% of undiagnosed cases. .",

keywords = "Hidradenitis suppurativa, Indonesia, Multicenter, Prevalence, Questionnaire, Cross-Sectional Studies, Humans, Middle Aged, Hidradenitis Suppurativa/epidemiology, Indonesia/epidemiology, Male, Young Adult, Female, Adult, Surveys and Questionnaires, Mass Screening/methods",

author = "Dewi, \{Shinta Trilaksmi\} and Nyoman Suryawati and Niken Indrastuti and Dorra Bouazzi and Medianfar, \{Cecilia E\} and Robin Christensen and Jemec, \{Gregor B E\} and Chandran, \{Nisha S\} and Miranti Pangastuti and Aryani Adji and Gardenia Akhyar and Nopriyati Nopriyati and Hazlianda, \{Cut Putri\} and Febriana, \{Sri Awalia\}",

note = "{\textcopyright} 2025 The Author(s). Published by S. Karger AG, Basel.",

year = "2025",

doi = "10.1159/000539705",

language = "English",

volume = "241",

pages = "57--62",

journal = "Dermatology",

issn = "1018-8665",

publisher = "S. Karger AG",

number = "Suppl. 1",

}

Dewi, ST, Suryawati, N, Indrastuti, N, Bouazzi, D, Medianfar, CE, Christensen, R, Jemec, GBE, Chandran, NS, Pangastuti, M, Adji, A, Akhyar, G, Nopriyati, N, Hazlianda, CP & Febriana, SA 2025, 'Hidradenitis Suppurativa Prevalence in Indonesia: A Cross-Sectional Multicenter Study and Validation of a Screening Questionnaire', Dermatology, vol. 241, no. Suppl. 1, pp. 57-62. https://doi.org/10.1159/000539705

TY - JOUR

T1 - Hidradenitis Suppurativa Prevalence in Indonesia

T2 - A Cross-Sectional Multicenter Study and Validation of a Screening Questionnaire

AU - Dewi, Shinta Trilaksmi

AU - Suryawati, Nyoman

AU - Indrastuti, Niken

AU - Bouazzi, Dorra

AU - Medianfar, Cecilia E

AU - Christensen, Robin

AU - Jemec, Gregor B E

AU - Chandran, Nisha S

AU - Pangastuti, Miranti

AU - Adji, Aryani

AU - Akhyar, Gardenia

AU - Nopriyati, Nopriyati

AU - Hazlianda, Cut Putri

AU - Febriana, Sri Awalia

PY - 2025

Y1 - 2025

N2 - UNLABELLED: Introduction: Studies on the prevalence of hidradenitis suppurative (HS) in Southeast Asia are scarce, and no studies have been conducted in Indonesia. This study aimed to calculate the prevalence of HS in Indonesia and validate this questionnaire in our population as part of the Global Hidradenitis Suppurativa Atlas (GHiSA) initiative.METHODS: This multicenter cross-sectional study was conducted at 7 teaching hospitals in western and central Indonesia from December 2022 to June 2023. A total of 3,237 healthy adults accompanying patients in the outpatient clinics consented to participate. Physicians or nurses delivered the validated screening questionnaire, and photos of the axilla and groin were taken from screen-positive individuals and 10% of the screen-negative individuals. The dermatologist examined the clinical photos to confirm the diagnosis of HS.RESULTS: The prevalence of HS in our study population was 0.43% (14/3,237; with 95% confidence interval [CI]: 0.26%-0.72%), and there was no significant difference in gender, age, body mass index (BMI), and smoking habit between the HS and non-HS groups. In the HS group, males and females were equally affected, with the median age being 29 years with interquartile range (IQR: 24.8-38.5), median BMI of 23.0 (IQR: 21.1-26.4), and 28.6% being smokers. The screening questionnaire showed a sensitivity of 0.43 (6/14; 95% CI: 0.18-0.17), specificity of 0.94 (362/386; 95% CI: 0.91-0.96), positive predictive value of 0.20 (6/30; 95% CI: 0.08-0.39), and negative predictive value of 0.98 (362/370; 95% CI: 0.96-0.99).CONCLUSION: The prevalence of HS in Indonesia is 0.43%, slightly lower than those reported in other Southeast Asian countries. Age, gender, BMI, and smoking habits were not risk factors for HS in our population. The questionnaire is moderately accurate for screening HS but remains valuable in detecting around 50% of undiagnosed cases. .

AB - UNLABELLED: Introduction: Studies on the prevalence of hidradenitis suppurative (HS) in Southeast Asia are scarce, and no studies have been conducted in Indonesia. This study aimed to calculate the prevalence of HS in Indonesia and validate this questionnaire in our population as part of the Global Hidradenitis Suppurativa Atlas (GHiSA) initiative.METHODS: This multicenter cross-sectional study was conducted at 7 teaching hospitals in western and central Indonesia from December 2022 to June 2023. A total of 3,237 healthy adults accompanying patients in the outpatient clinics consented to participate. Physicians or nurses delivered the validated screening questionnaire, and photos of the axilla and groin were taken from screen-positive individuals and 10% of the screen-negative individuals. The dermatologist examined the clinical photos to confirm the diagnosis of HS.RESULTS: The prevalence of HS in our study population was 0.43% (14/3,237; with 95% confidence interval [CI]: 0.26%-0.72%), and there was no significant difference in gender, age, body mass index (BMI), and smoking habit between the HS and non-HS groups. In the HS group, males and females were equally affected, with the median age being 29 years with interquartile range (IQR: 24.8-38.5), median BMI of 23.0 (IQR: 21.1-26.4), and 28.6% being smokers. The screening questionnaire showed a sensitivity of 0.43 (6/14; 95% CI: 0.18-0.17), specificity of 0.94 (362/386; 95% CI: 0.91-0.96), positive predictive value of 0.20 (6/30; 95% CI: 0.08-0.39), and negative predictive value of 0.98 (362/370; 95% CI: 0.96-0.99).CONCLUSION: The prevalence of HS in Indonesia is 0.43%, slightly lower than those reported in other Southeast Asian countries. Age, gender, BMI, and smoking habits were not risk factors for HS in our population. The questionnaire is moderately accurate for screening HS but remains valuable in detecting around 50% of undiagnosed cases. .

KW - Hidradenitis suppurativa

KW - Indonesia

KW - Multicenter

KW - Prevalence

KW - Questionnaire

KW - Cross-Sectional Studies

KW - Humans

KW - Middle Aged

KW - Hidradenitis Suppurativa/epidemiology

KW - Indonesia/epidemiology

KW - Male

KW - Young Adult

KW - Female

KW - Adult

KW - Surveys and Questionnaires

KW - Mass Screening/methods

U2 - 10.1159/000539705

DO - 10.1159/000539705

M3 - Article

C2 - 40623394

SN - 1018-8665

VL - 241

SP - 57

EP - 62

JO - Dermatology

JF - Dermatology

IS - Suppl. 1

ER -

Hidradenitis Suppurativa Prevalence in Indonesia: A Cross-Sectional Multicenter Study and Validation of a Screening Questionnaire

Abstract

Keywords

Access to Document

Fingerprint

Cite this