Etiology and epidemiology of catheter related bloodstream infections in patients receiving home parenteral nutrition in a gastromedical center at a tertiary hospital in Denmark

Xiaohui Chen Nielsen, Ming Chen, Anne Marie Blok Hellesøe, Palle Bekker Jeppesen, Jonna Gyldenlykke, Michael Tvede, Leif Percival Andersen

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Abstract

We conducted a retrospective epidemiologic study of catheter related bloodstream infections (CRBSI) in pa-tients receiving long-term home parenteral nutrition (HPN) from January 2002 to December 2005. Our results showed that coagulase negative staphylococci (CoNS) were the most prevalent pathogens (44.7% of all CRBSI episodes), followed by Enterobacteriaceae (33.2%). Prevalence for candidemia and Enterococcus bacteremia was relatively high (14.4% and 10.8%, respectively). Cefuroxime resistance was observed in 65.4% CoNS and 31.5% Entero bacteriaceae. Based on the results from the study, a new empiric antimicrobial treatment regiment was suggested.

Original languageEnglish
Pages (from-to)98-101
Number of pages4
JournalOpen Microbiology Journal
Volume6
Issue number1
DOIs
Publication statusPublished - 1 Dec 2012

Keywords

  • Antimicrobial susceptibility
  • Blood stream infection
  • Epidemiology
  • Etiology
  • Home parenteral nutrition
  • Intravascular catheter

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