A modified Nottingham Prognostic Index for breast cancer patients diagnosed in Denmark 1978-1994

Klaus Rostgaard; Henning T. Mouridsen; Michael Væth; Helle Holst; Knud P. Olesen; Elsebeth Lynge

doi:10.1080/02841860152703463

A modified Nottingham Prognostic Index for breast cancer patients diagnosed in Denmark 1978-1994

Klaus Rostgaard
, Henning T. Mouridsen
, Michael Væth
, Helle Holst
, Knud P. Olesen
, Elsebeth Lynge^*

^*Corresponding author for this work

Research output: Contribution to journal › Article › Research › peer-review

Abstract

Stage of disease at diagnosis is a predictor of breast cancer survival. We used data from the Danish Cancer Register and the Danish Breast Cancer Cooperative Group to study stage distribution in 0-69-year-old Danish breast cancer patients diagnosed in 1978-1994. We constructed a modified Nottingham Prognostic Index (NPI) calculated from the number of excised and positive lymph nodes, malignancy grade and tumour diameter. This NPI could be calculated for 63% of the patients, and among these the stage distribution improved during the study period. The proportion of patients with a poor prognostic score decreased from 27% to 20%. Based on a comparison of the crude 3-year survival of patients with an NPI score and those without, it seems probable that the stage of disease at diagnosis on average improved in Danish breast cancer patients below age 70 during the 1980s and the early 1990s.

Original language	English
Pages (from-to)	838-843
Number of pages	6
Journal	Acta Oncologica
Volume	40
Issue number	7
DOIs	https://doi.org/10.1080/02841860152703463
Publication status	Published - 1 Dec 2001

Funding

The project was Ž naniallcy supported by the M. LJør.ensegn & Gunnar Hnsen aFd; utehAnrtuhr &PaaSønduelard gFrua;nd the ChrtinisHaansen & Ellen Hansen Fund; the Lykfeldt Fund; and the RubianEe ElibnlthieIsvan Fer.usne d

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title = "A modified Nottingham Prognostic Index for breast cancer patients diagnosed in Denmark 1978-1994",

abstract = "Stage of disease at diagnosis is a predictor of breast cancer survival. We used data from the Danish Cancer Register and the Danish Breast Cancer Cooperative Group to study stage distribution in 0-69-year-old Danish breast cancer patients diagnosed in 1978-1994. We constructed a modified Nottingham Prognostic Index (NPI) calculated from the number of excised and positive lymph nodes, malignancy grade and tumour diameter. This NPI could be calculated for 63\% of the patients, and among these the stage distribution improved during the study period. The proportion of patients with a poor prognostic score decreased from 27\% to 20\%. Based on a comparison of the crude 3-year survival of patients with an NPI score and those without, it seems probable that the stage of disease at diagnosis on average improved in Danish breast cancer patients below age 70 during the 1980s and the early 1990s.",

author = "Klaus Rostgaard and Mouridsen, \{Henning T.\} and Michael V{\ae}th and Helle Holst and Olesen, \{Knud P.\} and Elsebeth Lynge",

year = "2001",

month = dec,

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doi = "10.1080/02841860152703463",

language = "English",

volume = "40",

pages = "838--843",

journal = "Acta Oncologica",

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TY - JOUR

T1 - A modified Nottingham Prognostic Index for breast cancer patients diagnosed in Denmark 1978-1994

AU - Rostgaard, Klaus

AU - Mouridsen, Henning T.

AU - Væth, Michael

AU - Holst, Helle

AU - Olesen, Knud P.

AU - Lynge, Elsebeth

PY - 2001/12/1

Y1 - 2001/12/1

N2 - Stage of disease at diagnosis is a predictor of breast cancer survival. We used data from the Danish Cancer Register and the Danish Breast Cancer Cooperative Group to study stage distribution in 0-69-year-old Danish breast cancer patients diagnosed in 1978-1994. We constructed a modified Nottingham Prognostic Index (NPI) calculated from the number of excised and positive lymph nodes, malignancy grade and tumour diameter. This NPI could be calculated for 63% of the patients, and among these the stage distribution improved during the study period. The proportion of patients with a poor prognostic score decreased from 27% to 20%. Based on a comparison of the crude 3-year survival of patients with an NPI score and those without, it seems probable that the stage of disease at diagnosis on average improved in Danish breast cancer patients below age 70 during the 1980s and the early 1990s.

AB - Stage of disease at diagnosis is a predictor of breast cancer survival. We used data from the Danish Cancer Register and the Danish Breast Cancer Cooperative Group to study stage distribution in 0-69-year-old Danish breast cancer patients diagnosed in 1978-1994. We constructed a modified Nottingham Prognostic Index (NPI) calculated from the number of excised and positive lymph nodes, malignancy grade and tumour diameter. This NPI could be calculated for 63% of the patients, and among these the stage distribution improved during the study period. The proportion of patients with a poor prognostic score decreased from 27% to 20%. Based on a comparison of the crude 3-year survival of patients with an NPI score and those without, it seems probable that the stage of disease at diagnosis on average improved in Danish breast cancer patients below age 70 during the 1980s and the early 1990s.

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DO - 10.1080/02841860152703463

M3 - Article

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AN - SCOPUS:0035686619

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EP - 843

JO - Acta Oncologica

JF - Acta Oncologica

IS - 7

ER -

A modified Nottingham Prognostic Index for breast cancer patients diagnosed in Denmark 1978-1994

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