Troværdig klinisk forskning kræver konsensus om effektmål

Linnea Rishøj Thorlacius, Bente Villumsen, Robin Christensen, Gregor B. E. Jemec

Publikation: Bidrag til tidsskriftArtikelForskningpeer review


In clinical studies, beneficial and harmful effects of interventions are investigated by measuring predefined outcomes. The uncontrolled choice of these outcomes carries a risk of outcome reporting bias, large heterogeneity of outcomes with reduced options for evidence synthesis. Furthermore, such outcomes may not be important for stakeholders including patients. A potential solution to these problems is to develop a core outcome set (COS) - a list of outcomes which have been estimated to be important to include in all future studies in a given setting by all relevant stakeholders. This review summarises the benefits of defining a COS.

Bidragets oversatte titelCredibility of clinical research depends on consensus on outcomes
Antal sider9
TidsskriftUgeskrift for Laeger
Udgave nummer33
StatusUdgivet - 14 aug. 2023


  • Bias
  • Biomedical Research
  • Consensus
  • Humans


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