Abstract
In clinical studies, beneficial and harmful effects of interventions are investigated by measuring predefined outcomes. The uncontrolled choice of these outcomes carries a risk of outcome reporting bias, large heterogeneity of outcomes with reduced options for evidence synthesis. Furthermore, such outcomes may not be important for stakeholders including patients. A potential solution to these problems is to develop a core outcome set (COS) - a list of outcomes which have been estimated to be important to include in all future studies in a given setting by all relevant stakeholders. This review summarises the benefits of defining a COS.
Bidragets oversatte titel | Credibility of clinical research depends on consensus on outcomes |
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Originalsprog | Dansk |
Artikelnummer | V09220579 |
Antal sider | 9 |
Tidsskrift | Ugeskrift for Laeger |
Vol/bind | 185 |
Udgave nummer | 33 |
Status | Udgivet - 14 aug. 2023 |
Emneord
- Bias
- Biomedical Research
- Consensus
- Humans