Transition of Myelofibrosis to Polycythaemia Vera

Hans Hasselbalch*, Dag Berild

*Corresponding author af dette arbejde

    Publikation: Bidrag til tidsskriftArtikelForskningpeer review

    Abstrakt

    A case of typical myelofibrosis with a huge spleen is described in a 62‐year‐old man. During the subsequent 2‐year follow‐up, a clinical picture of polycythaemia vera with pancytosis and disappearance of the marrow fibrosis was observed. The pancytosis necessitated treatment with busulphan and frequent phlebotomies. The transformation was associated with prednisone treatment for a suspected haemolytic state. During this treatment, the spleen no longer became enlarged on clinical palpation, although it was still enlarged at post mortem examination, but much less than 2 years earlier.

    OriginalsprogEngelsk
    Sider (fra-til)161-166
    Antal sider6
    TidsskriftScandinavian Journal of Haematology
    Vol/bind30
    Udgave nummer2
    DOI
    StatusUdgivet - feb. 1983

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