Time to consider ACE insertion/deletion genotypes and individual renoprotective treatment in diabetic nephropathy?

P. K. Jacobsen, L. Tarnow, H. H. Parving

    Publikation: Bidrag til tidsskriftKommentar/debatForskning

    Abstrakt

    One reason for the inadequacy of current renoprotective therapy and the persistent poor renal prognosis in diabetic nephropathy is the large interindividual variation in response to treatment. Genetic as well as non-genetic factors are known to influence treatment efficacy. This Commentary summarizes the impact of the angiotensin-converting enzyme (ACE) insertion/deletion polymorphism in the ACE gene on initiation and progression of diabetic nephropathy.

    OriginalsprogEngelsk
    Sider (fra-til)1293-1295
    Antal sider3
    TidsskriftKidney International
    Vol/bind69
    Udgave nummer8
    DOI
    StatusUdgivet - apr. 2006

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