Thrombocytopenia, antithrombin deficiency and extensive thromboembolism in pregnancy: Treatment with low-molecular-weight heparin

N. S. Macklon*, I. A. Greer, A. W. Reid, I. D. Walker

*Corresponding author af dette arbejde

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    Abstrakt

    Pregnancy limits the therapeutic options for managing thrombocytopenia which occurs in 5% of patients on heparin. We describe a case of extensive thromboembolism associated with antithrombin (AT) deficiency complicated by thrombocytopenia which resol ed when low-molecular-weight heparin was instituted A primigravid woman presented at 11 weeks gestation with bilateral femoral occlusive thrombi extending above the renal veins. Investigations revealed AT deficiency, thrombocytopenia and renal infarction After low-molecular-weight heparin was substituted for unfractionated heparin, the thrombocytopenia resolved and although the pregnancy was lost, the patient made a full recovery.

    OriginalsprogEngelsk
    Sider (fra-til)672-675
    Antal sider4
    TidsskriftBlood Coagulation and Fibrinolysis
    Vol/bind6
    Udgave nummer7
    DOI
    StatusUdgivet - 1 jan. 1995

    Fingeraftryk

    Udforsk hvilke forskningsemner 'Thrombocytopenia, antithrombin deficiency and extensive thromboembolism in pregnancy: Treatment with low-molecular-weight heparin' indeholder.

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