The role of therapy in impairing quality of life in dermatological patients: A multinational study

Flora N. Balieva*, Andrew Y. Finlay, Jörg Kupfer, Lucia Tomas Aragones, Lars Lien, Uwe Gieler, Francoise Poot, Gregor B.E. Jemec, Laurent Misery, Lajos Kemeny, Francesca Sampogna, Henriët Van Middendorp, Jon Anders Halvorsen, Thomas Ternowitz, Jacek C. Szepietowski, Nikolay Potekaev, Servando E. Marron, Ilknur K. Altunay, Sam S. Salek, Florence J. Dalgard

*Corresponding author af dette arbejde

Publikation: Bidrag til tidsskriftArtikelForskningpeer review

Abstract

Skin disease and its therapy affect health-related quality of life (HRQoL). The aim of this study was to measure the burden caused by dermatological therapy in 3,846 patients from 13 European countries. Adult outpatients completed questionnaires, including the Dermatology Life Quality Index (DLQI), which has a therapy impact question. Therapy issues were reported by a majority of patients with atopic dermatitis (63.4%), psoriasis (60.7%), prurigo (54.4%), hidradenitis suppurativa (54.3%) and blistering conditions (53%). The largest reduction in HRQoL attributable to therapy, as a percentage of total DLQI, adjusted for confounders, was seen in blistering conditions (10.7%), allergic/ drug reactions (10.2%), psoriasis (9.9%), vasculi-tis/immunological ulcers (8.8%), atopic dermatitis (8.7%), and venous leg ulcers (8.5%). In skin cancer, although it had less impact on HRQoL, the reduction due to therapy was 6.8%. Treatment for skin disease contributes considerably to reducing HRQoL: the burden of dermatological treatment should be considered when planning therapy and designing new dermatological therapies.

OriginalsprogEngelsk
Sider (fra-til)563-569
Antal sider7
TidsskriftActa Dermato-Venereologica
Vol/bind98
Udgave nummer6
DOI
StatusUdgivet - jun. 2018

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