The origin of the 1.73-m2 body surface area normalization: Problems and implications

James G. Heaf*

*Corresponding author af dette arbejde

    Publikation: Bidrag til tidsskriftReviewForskningpeer review

    Abstract

    A historical review of the origins of body surface area (BSA) determination reveals a number of theoretical and methodological errors, as does the choice of 1.73 m2 as the normal BSA for humans. BSA normalization is justifiable for some physiological variables, e.g. glomerular filtration rate and cardiac output, but not all. However, other normalization indices, in particular extracellular volume, offer theoretical and practical advantages compared with BSA. While the choice of the figure 1.73 m2 is essentially arbitrary, and inapplicable to modern Western populations, its retention as a permanent physiological constant is recommended, in order to permit international and historical comparisons.

    OriginalsprogEngelsk
    Sider (fra-til)135-137
    Antal sider3
    TidsskriftClinical Physiology and Functional Imaging
    Vol/bind27
    Udgave nummer3
    DOI
    StatusUdgivet - 1 maj 2007

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