The impact of ultraviolet therapy on stratum corneum ceramides and barrier function

Jakob Mutanu Jungersted; Julie K. Høgh; Lars I. Hellgren; Gregor B.E. Jemec; Tove Agner

doi:10.1111/j.1600-0781.2011.00618.x

The impact of ultraviolet therapy on stratum corneum ceramides and barrier function

Jakob Mutanu Jungersted^*, Julie K. Høgh, Lars I. Hellgren, Gregor B.E. Jemec, Tove Agner

^*Corresponding author af dette arbejde

Dermatologisk Afdeling

Publikation: Bidrag til tidsskrift › Artikel › Forskning › peer review

Abstract

The ceramide profile as well as the barrier function is known to be deteriorated in atopic eczema and psoriasis, and ultraviolet (UV) light is known to improve the barrier function. The impact of UV light on ceramides, however, is not clarified. The aim of this study was to examine the effect of UV therapy in dermatological patients on ceramides and skin barrier function. We found that UV light treatment does not change the ratio of important stratum corneum lipids, but we confirm earlier findings of decreased susceptibility to irritants after UV- therapy.

Originalsprog	Engelsk
Sider (fra-til)	331-333
Antal sider	3
Tidsskrift	Photodermatology Photoimmunology and Photomedicine
Vol/bind	27
Udgave nummer	6
DOI	https://doi.org/10.1111/j.1600-0781.2011.00618.x
Status	Udgivet - 1 dec. 2011

Adgang til dokumentet

10.1111/j.1600-0781.2011.00618.x

Andre filer og links

http://www.scopus.com/inward/record.url?scp=81355151457&partnerID=8YFLogxK

Citationsformater

@article{e0ecb7c4d80b42d9ac238eed1ee0f863,

title = "The impact of ultraviolet therapy on stratum corneum ceramides and barrier function",

abstract = "The ceramide profile as well as the barrier function is known to be deteriorated in atopic eczema and psoriasis, and ultraviolet (UV) light is known to improve the barrier function. The impact of UV light on ceramides, however, is not clarified. The aim of this study was to examine the effect of UV therapy in dermatological patients on ceramides and skin barrier function. We found that UV light treatment does not change the ratio of important stratum corneum lipids, but we confirm earlier findings of decreased susceptibility to irritants after UV- therapy.",

keywords = "Ceramides, Skin barrier measurements, UV light therapy",

author = "Jungersted, {Jakob Mutanu} and H{\o}gh, {Julie K.} and Hellgren, {Lars I.} and Jemec, {Gregor B.E.} and Tove Agner",

year = "2011",

month = dec,

day = "1",

doi = "10.1111/j.1600-0781.2011.00618.x",

language = "English",

volume = "27",

pages = "331--333",

journal = "Photodermatology Photoimmunology and Photomedicine",

issn = "0905-4383",

publisher = "Blackwell Munksgaard",

number = "6",

}

TY - JOUR

T1 - The impact of ultraviolet therapy on stratum corneum ceramides and barrier function

AU - Jungersted, Jakob Mutanu

AU - Høgh, Julie K.

AU - Hellgren, Lars I.

AU - Jemec, Gregor B.E.

AU - Agner, Tove

PY - 2011/12/1

Y1 - 2011/12/1

N2 - The ceramide profile as well as the barrier function is known to be deteriorated in atopic eczema and psoriasis, and ultraviolet (UV) light is known to improve the barrier function. The impact of UV light on ceramides, however, is not clarified. The aim of this study was to examine the effect of UV therapy in dermatological patients on ceramides and skin barrier function. We found that UV light treatment does not change the ratio of important stratum corneum lipids, but we confirm earlier findings of decreased susceptibility to irritants after UV- therapy.

AB - The ceramide profile as well as the barrier function is known to be deteriorated in atopic eczema and psoriasis, and ultraviolet (UV) light is known to improve the barrier function. The impact of UV light on ceramides, however, is not clarified. The aim of this study was to examine the effect of UV therapy in dermatological patients on ceramides and skin barrier function. We found that UV light treatment does not change the ratio of important stratum corneum lipids, but we confirm earlier findings of decreased susceptibility to irritants after UV- therapy.

KW - Ceramides

KW - Skin barrier measurements

KW - UV light therapy

UR - http://www.scopus.com/inward/record.url?scp=81355151457&partnerID=8YFLogxK

U2 - 10.1111/j.1600-0781.2011.00618.x

DO - 10.1111/j.1600-0781.2011.00618.x

M3 - Article

C2 - 22092739

AN - SCOPUS:81355151457

SN - 0905-4383

VL - 27

SP - 331

EP - 333

JO - Photodermatology Photoimmunology and Photomedicine

JF - Photodermatology Photoimmunology and Photomedicine

IS - 6

ER -

The impact of ultraviolet therapy on stratum corneum ceramides and barrier function

Abstract

Adgang til dokumentet

Andre filer og links

Fingeraftryk

Citationsformater