TY - JOUR
T1 - The effect of hyperbaric oxygen therapy in head and neck cancer patients with radiation induced dysphagia-a systematic review
AU - Philipsen, Bahareh Bakhshaie
AU - Korsholm, Malene
AU - Rohde, Max
AU - Wessel, Irene
AU - Forner, Lone
AU - Johansen, Jørgen
AU - Godballe, Christian
N1 - © 2024. The Author(s), under exclusive licence to Federación de Sociedades Españolas de Oncología (FESEO).
PY - 2024/10
Y1 - 2024/10
N2 - PURPOSE: The aim of this systematic review was to assess the role of hyperbaric oxygen therapy (HBOT) in patients with dysphagia after radiation therapy for head and neck cancer.METHOD: A systematic search was conducted in the electronic databases Ovid MEDLINE, Ovid Embase, and Cochrane Central Register of Controlled Trials for relevant studies until March 14, 2023. No restriction on language or publication date. The criteria for inclusion: patients with HNC who had received both radiation therapy and HBOT as 1) a preventive treatment against swallowing difficulties, 2) to preserve swallowing function, or 3) to promote swallowing difficulties.RESULTS: We identified 1396 records. After removal of 31 duplicates, 1365 records were accessible for title and abstract screening. This yielded 53 studies for full text assessment. Six studies met the eligibility criteria and were included for qualitative analysis.CONCLUSION: Evidence of HBOT benefits in patients with dysphagia after radiation therapy for head and neck cancer is inconsistent. Well-designed studies using validated outcome measures and long-term follow-up are warranted.
AB - PURPOSE: The aim of this systematic review was to assess the role of hyperbaric oxygen therapy (HBOT) in patients with dysphagia after radiation therapy for head and neck cancer.METHOD: A systematic search was conducted in the electronic databases Ovid MEDLINE, Ovid Embase, and Cochrane Central Register of Controlled Trials for relevant studies until March 14, 2023. No restriction on language or publication date. The criteria for inclusion: patients with HNC who had received both radiation therapy and HBOT as 1) a preventive treatment against swallowing difficulties, 2) to preserve swallowing function, or 3) to promote swallowing difficulties.RESULTS: We identified 1396 records. After removal of 31 duplicates, 1365 records were accessible for title and abstract screening. This yielded 53 studies for full text assessment. Six studies met the eligibility criteria and were included for qualitative analysis.CONCLUSION: Evidence of HBOT benefits in patients with dysphagia after radiation therapy for head and neck cancer is inconsistent. Well-designed studies using validated outcome measures and long-term follow-up are warranted.
KW - Deglutition Disorders/etiology
KW - Head and Neck Neoplasms/radiotherapy
KW - Humans
KW - Hyperbaric Oxygenation/methods
KW - Radiation Injuries/therapy
U2 - 10.1007/s12094-024-03449-w
DO - 10.1007/s12094-024-03449-w
M3 - Review
C2 - 38704813
SN - 1699-048X
VL - 26
SP - 2594
EP - 2600
JO - Clinical and Translational Oncology
JF - Clinical and Translational Oncology
IS - 10
ER -