Ten-year retrospective study of head and neck carcinoma in situ: Incidence, treatment, and clinical outcome

A. Christensen, E. Kristensen, M. H. Therkildsen, L. Specht, J. Reibel, P. Homøe

Publikation: Bidrag til tidsskriftArtikelForskningpeer review

Abstrakt

Objectives: To examine the management and clinical outcome for patients with primary head and neck carcinoma in situ (CIS) and to estimate the incidence in the referral population. Study design: A retrospective study from 2000-2009 of patients with head and neck CIS referred for treatment at Rigshospitalet. The referral area was East Denmark and Greenland with a population of 2.4 million. Results: Fifty-five patients with primary CIS were identified: 21 oral cavity, 7 pharynx, 25 larynx, 2 nasal cavity/paranasal sinuses. The median annual incidence was 0.24/100,000. Eleven patients (20%) had T-site recurrence. The 5-year disease-specific survival rate and 5-year recurrence-free survival rate were 98% and 74% respectively. Conclusions: The annual incidence of primary head and neck CIS was low and in accordance with previous findings reported in the literature. We recommend that CIS lesions should be treated on T-site and surveilled as T1/T2 head and neck carcinomas.

OriginalsprogEngelsk
Sider (fra-til)174-178
Antal sider5
TidsskriftOral Surgery, Oral Medicine, Oral Pathology and Oral Radiology
Vol/bind116
Udgave nummer2
DOI
StatusUdgivet - 1 aug. 2013
Udgivet eksterntJa

Fingeraftryk Udforsk hvilke forskningsemner 'Ten-year retrospective study of head and neck carcinoma in situ: Incidence, treatment, and clinical outcome' indeholder.

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