Study design, participation and characteristics of the danish general suburban population study

Helle K.M. Bergholdt, Lise Bathum, Jan Kvetny, Dorthe B. Rasmussen, Birgitte Moldow, Tracy Hoeg, Gregor B.E. Jemec, Helle Berner-Nielsen, Børge G. Nordestgaard, Christina Ellervik

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Abstrakt

INTRODUCTION: The aim of this article was to describe the study design, participants and baseline characteristics of The Danish General Suburban Population Study (GESUS) and to compare suburban participants with age- and gender-matched urban participants from the Copenhagen General Population Study (CGPS). MATERIAL AND METHODS: Data from questionnaire, health examination, biochemical measurements and public registers were collected. RESULTS: In GESUS the overall participation rate was 49.3% (response n = 10,621 of total n = 21,557). Among people aged 40-79 years, the participation rate was 53.9% (8,797/16,310). Participants were more frequently women, had a higher median age, a higher frequency of marriage/ registered partnerships, but had a lower frequency of comorbidities and death in the follow-up period (January 2010May 2011 (diseases)/June 2011 (death) than the non-participants. GESUS has sufficient power to study effects of rare and common exposures or genetic variants on the occurrence of common multifactorial diseases. Compared with an age- and gender-matched urban population (n = 10,618, CGPS), participants in GESUS (n = 10,618) were less physically active, smoked less and ingested less alcohol, had higher anthropometric measures, less undiagnosed hypertension but more undiagnosed diabetes, had a lower frequency of elevated total cholesterol and low-density lipoprotein cholesterol but higher frequency of decreased high-density lipoprotein cholesterol and elevated triglycerides. CONCLUSION: In GESUS, participants had a better health profile than non-participants, and participants in GESUS had a different cardiovascular risk profile than participants in participants in the CGPS.

OriginalsprogEngelsk
ArtikelnummerA4693
TidsskriftDanish medical journal
Vol/bind60
Udgave nummer9
StatusUdgivet - 1 sep. 2013

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