Studies of association of the CASQ1 rs2275703 polymorphism in relation to type 2 diabetes and related quantitative metabolic traits among 7088 Danish whites

Thomas Sparsø, Meena Shaheen Hussain, Knut Borch-Johnsen, Torben Jørgensen, Sten Madsbad, Torben Hansen, Oluf Pedersen, Gitte Andersen

    Publikation: Bidrag til tidsskriftArtikelForskningpeer review

    Abstrakt

    Calsequestrin 1 (CASQ1) is a calcium storage protein of fast-twitch skeletal muscle cells. In previous human association studies the results have been contradictory regarding the association between a CASQ1 rs2275703 polymorphism and type 2 diabetes. In the present study of the CASQ1 rs2275703 polymorphism in 7088 Danish whites the allele frequency and genotype distribution did not differ between type 2 diabetic patients and glucose-tolerant control subjects, neither was found any association with diabetes-related quantitative traits.

    OriginalsprogEngelsk
    Sider (fra-til)278-282
    Antal sider5
    TidsskriftMolecular Genetics and Metabolism
    Vol/bind92
    Udgave nummer3
    DOI
    StatusUdgivet - 1 nov. 2007

    Fingeraftryk Udforsk hvilke forskningsemner 'Studies of association of the CASQ1 rs2275703 polymorphism in relation to type 2 diabetes and related quantitative metabolic traits among 7088 Danish whites' indeholder.

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