Studies of association of the CASQ1 rs2275703 polymorphism in relation to type 2 diabetes and related quantitative metabolic traits among 7088 Danish whites

Thomas Sparsø; Meena Shaheen Hussain; Knut Borch-Johnsen; Torben Jørgensen; Sten Madsbad; Torben Hansen; Oluf Pedersen; Gitte Andersen

doi:10.1016/j.ymgme.2007.06.011

Studies of association of the CASQ1 rs2275703 polymorphism in relation to type 2 diabetes and related quantitative metabolic traits among 7088 Danish whites

Thomas Sparsø, Meena Shaheen Hussain, Knut Borch-Johnsen, Torben Jørgensen, Sten Madsbad, Torben Hansen, Oluf Pedersen, Gitte Andersen

Publikation: Bidrag til tidsskrift › Artikel › Forskning › peer review

Abstrakt

Calsequestrin 1 (CASQ1) is a calcium storage protein of fast-twitch skeletal muscle cells. In previous human association studies the results have been contradictory regarding the association between a CASQ1 rs2275703 polymorphism and type 2 diabetes. In the present study of the CASQ1 rs2275703 polymorphism in 7088 Danish whites the allele frequency and genotype distribution did not differ between type 2 diabetic patients and glucose-tolerant control subjects, neither was found any association with diabetes-related quantitative traits.

Originalsprog	Engelsk
Sider (fra-til)	278-282
Antal sider	5
Tidsskrift	Molecular Genetics and Metabolism
Vol/bind	92
Udgave nummer	3
DOI	https://doi.org/10.1016/j.ymgme.2007.06.011
Status	Udgivet - 1 nov. 2007

Adgang til dokumentet

10.1016/j.ymgme.2007.06.011

Andre filer og links

http://www.scopus.com/inward/record.url?scp=34848911646&partnerID=8YFLogxK

Fingeraftryk Udforsk hvilke forskningsemner 'Studies of association of the CASQ1 rs2275703 polymorphism in relation to type 2 diabetes and related quantitative metabolic traits among 7088 Danish whites' indeholder.

Citationsformater

Sparsø, T., Hussain, M. S., Borch-Johnsen, K., Jørgensen, T., Madsbad, S., Hansen, T., Pedersen, O., & Andersen, G. (2007). Studies of association of the CASQ1 rs2275703 polymorphism in relation to type 2 diabetes and related quantitative metabolic traits among 7088 Danish whites. Molecular Genetics and Metabolism, 92(3), 278-282. https://doi.org/10.1016/j.ymgme.2007.06.011

Sparsø, Thomas ; Hussain, Meena Shaheen ; Borch-Johnsen, Knut ; Jørgensen, Torben ; Madsbad, Sten ; Hansen, Torben ; Pedersen, Oluf ; Andersen, Gitte. / Studies of association of the CASQ1 rs2275703 polymorphism in relation to type 2 diabetes and related quantitative metabolic traits among 7088 Danish whites. I: Molecular Genetics and Metabolism. 2007 ; Bind 92, Nr. 3. s. 278-282.

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abstract = "Calsequestrin 1 (CASQ1) is a calcium storage protein of fast-twitch skeletal muscle cells. In previous human association studies the results have been contradictory regarding the association between a CASQ1 rs2275703 polymorphism and type 2 diabetes. In the present study of the CASQ1 rs2275703 polymorphism in 7088 Danish whites the allele frequency and genotype distribution did not differ between type 2 diabetic patients and glucose-tolerant control subjects, neither was found any association with diabetes-related quantitative traits.",

keywords = "Association, Calsequestrin, Obesity, Type 2 diabetes",

author = "Thomas Spars{\o} and Hussain, {Meena Shaheen} and Knut Borch-Johnsen and Torben J{\o}rgensen and Sten Madsbad and Torben Hansen and Oluf Pedersen and Gitte Andersen",

year = "2007",

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doi = "10.1016/j.ymgme.2007.06.011",

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Sparsø, T, Hussain, MS, Borch-Johnsen, K, Jørgensen, T, Madsbad, S, Hansen, T, Pedersen, O & Andersen, G 2007, 'Studies of association of the CASQ1 rs2275703 polymorphism in relation to type 2 diabetes and related quantitative metabolic traits among 7088 Danish whites', Molecular Genetics and Metabolism, bind 92, nr. 3, s. 278-282. https://doi.org/10.1016/j.ymgme.2007.06.011

Studies of association of the CASQ1 rs2275703 polymorphism in relation to type 2 diabetes and related quantitative metabolic traits among 7088 Danish whites. / Sparsø, Thomas; Hussain, Meena Shaheen; Borch-Johnsen, Knut; Jørgensen, Torben; Madsbad, Sten; Hansen, Torben; Pedersen, Oluf; Andersen, Gitte.

I: Molecular Genetics and Metabolism, Bind 92, Nr. 3, 01.11.2007, s. 278-282.

Publikation: Bidrag til tidsskrift › Artikel › Forskning › peer review

TY - JOUR

T1 - Studies of association of the CASQ1 rs2275703 polymorphism in relation to type 2 diabetes and related quantitative metabolic traits among 7088 Danish whites

AU - Sparsø, Thomas

AU - Hussain, Meena Shaheen

AU - Borch-Johnsen, Knut

AU - Jørgensen, Torben

AU - Madsbad, Sten

AU - Hansen, Torben

AU - Pedersen, Oluf

AU - Andersen, Gitte

PY - 2007/11/1

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N2 - Calsequestrin 1 (CASQ1) is a calcium storage protein of fast-twitch skeletal muscle cells. In previous human association studies the results have been contradictory regarding the association between a CASQ1 rs2275703 polymorphism and type 2 diabetes. In the present study of the CASQ1 rs2275703 polymorphism in 7088 Danish whites the allele frequency and genotype distribution did not differ between type 2 diabetic patients and glucose-tolerant control subjects, neither was found any association with diabetes-related quantitative traits.

AB - Calsequestrin 1 (CASQ1) is a calcium storage protein of fast-twitch skeletal muscle cells. In previous human association studies the results have been contradictory regarding the association between a CASQ1 rs2275703 polymorphism and type 2 diabetes. In the present study of the CASQ1 rs2275703 polymorphism in 7088 Danish whites the allele frequency and genotype distribution did not differ between type 2 diabetic patients and glucose-tolerant control subjects, neither was found any association with diabetes-related quantitative traits.

KW - Association

KW - Calsequestrin

KW - Obesity

KW - Type 2 diabetes

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U2 - 10.1016/j.ymgme.2007.06.011

DO - 10.1016/j.ymgme.2007.06.011

M3 - Article

C2 - 17681849

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EP - 282

JO - Molecular Genetics and Metabolism

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