Stratum corneum damage and ex vivo porcine skin water absorption - A pilot study

C. Duch Lynggaard*, D. Bang Knudsen, G. B.E. Jemec

*Corresponding author af dette arbejde

Publikation: Bidrag til tidsskriftLetterForskningpeer review

Abstrakt

A simple ex vivo screening technique would be of interest for mass screening of substances for potential barrier disruptive qualities. Ex vivo water absorption as a marker of skin barrier integrity was studied on pig ear skin. Skin water absorption was quantified by weighing and weight changes were found to reflect prehydration barrier damage. It is suggested that this simple model may be elaborated to provide a rapid, economical screening tool for potential skin irritants.

OriginalsprogEngelsk
Sider (fra-til)295-298
Antal sider4
TidsskriftSkin Pharmacology and Physiology
Vol/bind22
Udgave nummer6
DOI
StatusUdgivet - 1 nov. 2009

Fingeraftryk

Udforsk hvilke forskningsemner 'Stratum corneum damage and ex vivo porcine skin water absorption - A pilot study' indeholder.

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