TY - JOUR
T1 - Stationary facial nerve paresis after surgery for recurrent parotid pleomorphic adenoma
T2 - a follow-up study of 219 cases in Denmark in the period 1985–2012
AU - Nøhr, Anders
AU - Andreasen, Simon
AU - Therkildsen, Marianne Hamilton
AU - Homøe, Preben
PY - 2016/10/1
Y1 - 2016/10/1
N2 - The purpose was to assess degree of permanent facial nerve dysfunction after surgery for recurrent pleomorphic adenoma (RPA) of the parotid gland, including variables that might influence re-operation outcomes. Nationwide retrospective longitudinal cohort study including a questionnaire survey of patients undergoing surgery for RPA. Of 219 living patients, 198 (92 %) responded and 127 (63 %) reported no facial dysfunction. Statistically significant associations were found between number of surgeries and permanent facial nerve dysfunction of all degrees (OR 1.43, 95 % CI 1.16–1.78, p = 0.001). A not significant tendency for females to be associated with worse outcome was found (p = 0.073). Risks of different degrees of paresis after the second–fourth surgeries were found (OR 1.86–2.19, p < 0.05). Our study demonstrates a significant correlation between number of surgeries for RPA of the parotid and severity of facial nerve paresis. This is important when informing and planning treatment of these patients.
AB - The purpose was to assess degree of permanent facial nerve dysfunction after surgery for recurrent pleomorphic adenoma (RPA) of the parotid gland, including variables that might influence re-operation outcomes. Nationwide retrospective longitudinal cohort study including a questionnaire survey of patients undergoing surgery for RPA. Of 219 living patients, 198 (92 %) responded and 127 (63 %) reported no facial dysfunction. Statistically significant associations were found between number of surgeries and permanent facial nerve dysfunction of all degrees (OR 1.43, 95 % CI 1.16–1.78, p = 0.001). A not significant tendency for females to be associated with worse outcome was found (p = 0.073). Risks of different degrees of paresis after the second–fourth surgeries were found (OR 1.86–2.19, p < 0.05). Our study demonstrates a significant correlation between number of surgeries for RPA of the parotid and severity of facial nerve paresis. This is important when informing and planning treatment of these patients.
KW - Facial nerve paresis
KW - Morbidity
KW - Pleomorphic adenoma
KW - Recurrence
KW - Surgery
UR - http://www.scopus.com/inward/record.url?scp=84957676298&partnerID=8YFLogxK
U2 - 10.1007/s00405-016-3921-9
DO - 10.1007/s00405-016-3921-9
M3 - Article
C2 - 26869475
AN - SCOPUS:84957676298
SN - 0937-4477
VL - 273
SP - 3313
EP - 3319
JO - European Archives of Oto-Rhino-Laryngology
JF - European Archives of Oto-Rhino-Laryngology
IS - 10
ER -