TY - JOUR
T1 - Sleep Disturbances in Female Adolescents With Borderline Personality Disorder
T2 - A 5-Year Longitudinal Study
AU - Jørgensen, Mie Sedoc
AU - Cano, Kiana
AU - Sharp, Carla
AU - Bo, Sune
AU - Storebø, Ole Jakob
AU - Gøtzsche, Martin Vestergaard
AU - Møller, Lise
AU - Poulsen, Stig
AU - Beck, Emma
AU - Simonsen, Erik
N1 - © 2025 John Wiley & Sons Ltd.
PY - 2025/8
Y1 - 2025/8
N2 - Sleep disturbances are commonly reported in individuals with borderline personality disorder (BPD) and are often worsened by comorbid mental health disorders such as ADHD, PTSD, and depression. Sleep problems may contribute to the persistence of symptoms, highlighting the importance of early identification and treatment of sleep disturbances as part of early intervention strategies. Despite this, the prevalence and predictors of persistent sleep problems in the early course of BPD remain understudied, particularly in longitudinal designs. In this study, we followed up on 110 female adolescents with BPD pathology 5 years after being included in the study to investigate the prevalence and predictors of sleep problems collected using a semistructured interview as participants transitioned into early adulthood. At baseline, BPD severity, ADHD, and melatonin use were associated with sleep disturbances. However, at 5-year follow-up, baseline ADHD, depression severity, and melatonin use emerged as the strongest predictors of persistent sleep problems, while BPD severity was no longer predictive. These findings underscore the complex interplay between comorbid mental health disorders and the development and maintenance of sleep problems in BPD. Targeting adolescents with BPD and severe sleep disturbances requiring medical intervention, comorbid ADHD, and significant depressive symptoms is crucial for alleviating persistent sleep problems. Integrating specific sleep interventions into early treatment strategies represents sound clinical management in the early stages of BPD, and future research should explore whether targeted interventions for these risk factors can mitigate long-term sleep-related challenges and improve overall outcomes for individuals with BPD.
AB - Sleep disturbances are commonly reported in individuals with borderline personality disorder (BPD) and are often worsened by comorbid mental health disorders such as ADHD, PTSD, and depression. Sleep problems may contribute to the persistence of symptoms, highlighting the importance of early identification and treatment of sleep disturbances as part of early intervention strategies. Despite this, the prevalence and predictors of persistent sleep problems in the early course of BPD remain understudied, particularly in longitudinal designs. In this study, we followed up on 110 female adolescents with BPD pathology 5 years after being included in the study to investigate the prevalence and predictors of sleep problems collected using a semistructured interview as participants transitioned into early adulthood. At baseline, BPD severity, ADHD, and melatonin use were associated with sleep disturbances. However, at 5-year follow-up, baseline ADHD, depression severity, and melatonin use emerged as the strongest predictors of persistent sleep problems, while BPD severity was no longer predictive. These findings underscore the complex interplay between comorbid mental health disorders and the development and maintenance of sleep problems in BPD. Targeting adolescents with BPD and severe sleep disturbances requiring medical intervention, comorbid ADHD, and significant depressive symptoms is crucial for alleviating persistent sleep problems. Integrating specific sleep interventions into early treatment strategies represents sound clinical management in the early stages of BPD, and future research should explore whether targeted interventions for these risk factors can mitigate long-term sleep-related challenges and improve overall outcomes for individuals with BPD.
KW - Humans
KW - Borderline Personality Disorder/epidemiology
KW - Female
KW - Adolescent
KW - Longitudinal Studies
KW - Sleep Wake Disorders/epidemiology
KW - Comorbidity
KW - Melatonin/therapeutic use
KW - Attention Deficit Disorder with Hyperactivity/epidemiology
KW - Depression/epidemiology
KW - Severity of Illness Index
KW - Young Adult
KW - Prevalence
KW - Adhd
KW - Sleep disturbance
KW - Adolescence
KW - Melatonin
KW - Longitudinal
KW - Depression
KW - Borderline personality disorder
U2 - 10.1002/pmh.70031
DO - 10.1002/pmh.70031
M3 - Article
C2 - 40578824
SN - 1932-8621
VL - 19
JO - Personality and Mental Health
JF - Personality and Mental Health
IS - 3
M1 - e70031
ER -