Six cases of Aerococcus sanguinicola infection: Clinical relevance and bacterial identification

Kristina Ibler, Kjeld Truberg Jensen, Christian Østergaard, Ute Wolff Sönksen, Brita Bruun, Henrik C. Schønheyder, Michael Kemp, Rimtas Dargis, Keld Andresen, Jens Jørgen Christensen

    Publikation: Bidrag til tidsskriftArtikelForskningpeer review

    Abstrakt

    Aerococcus sanguinicola is a Gram-positive coccus first described in 2001. Infections in humans are rare but the use of 16S rRNA gene sequencing and improved phenotypic methods has facilitated the identification of A. sanguinicola. We report here 6 cases of A. sanguinicola bacteraemia, 2 of which were associated with infective endocarditis. Most patients were elderly (median age 70 y) and had underlying neurological disorders including dementia, cerebral degeneration, and myelomeningocele. The primary focus of infection was the urinary tract in 3 cases and the gallbladder in 1; no focus was detected in 2 cases. Long-term prognosis was poor reflecting the frailty of the patients. All strains were susceptible to penicillin, ampicillin, cefuroxime, vancomycin, erythromycin, and rifampicin. The optimal treatment of infection with A. sanguinicola has yet to be determined.

    OriginalsprogEngelsk
    Sider (fra-til)761-765
    Antal sider5
    TidsskriftScandinavian Journal of Infectious Diseases
    Vol/bind40
    Udgave nummer9
    DOI
    StatusUdgivet - 4 sep. 2008

    Fingeraftryk Udforsk hvilke forskningsemner 'Six cases of Aerococcus sanguinicola infection: Clinical relevance and bacterial identification' indeholder.

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