Salicylate poisoning in a centre for treatment of poisoning in 1980

P. A.L. Bjaeldager, L. Breum, L. K. Munck

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    Out of 1,330 patients suffering from poisoning admitted to the Centre for the Treatment of Poisoning in 1980, 153 had ingested salicylate. Thirty-three patients had pure salicylate poisoning while 120 suffered from mixed poisoning. Within the various drug classes, the patients were subdivided into poisoning levels from 0-4. In cases of mixed poisoning, salicylate was the most important medicament or as important as the other agent in 71 patients while it was less important in 49 patients; these latter are not included in the results. Poisoning levels 2 and 3 were found in 25/33 and 52/71 while 5/33 and 2/71 were level 4. 24/33 and 47/71 were women, 20/33 and 32/71 were aged 0-29 years. On admission, 29/33 and 54/71 were awake and only 4/104 were comatose. 19/33 and 32/71 had pulses ≥100 and of these 3/33 had pulse rates of 140-160. During hospitalization, 1/33 and 5/71 developed hypotension and 3/33 and 2/71 hypertension. 3/33 and 5/71 had slight reduction of renal function while 5/33 and 4/71 developed temperatures ≥38°C. 1/33 developed cardiac arrest but survived. 26/33 and 41/71 were treated with alkalization and forced diuresis and 17/33 and 36/71 with phytomenadion. Only five patients received blood or plasma and four received antibiotics. 27/33 and 64/71 could be discharged within the first 24 hours of hospitalization and the remainder during the second 24 hours. Four patients were hospitalized ≥120 hours on account of pulmonary aspiration or infection. Cases of salicylate poisoning which are diagnosed early and treated adequately present extremely few complications, brief periods of detoxication and a mortality which is practically non-existent.

    Sider (fra-til)2833-2837
    Antal sider5
    TidsskriftUgeskrift for laeger
    Udgave nummer37
    StatusUdgivet - 1 jan. 1983


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