TY - JOUR
T1 - Risk of asthma in adult twins with type 2 diabetes and increased body mass index
AU - Thomsen, Simon Francis
AU - Duffy, D L
AU - Kyvik, K O
AU - Skytthe, Axel
AU - Backer, Vibeke
N1 - © 2010 John Wiley Sons A/S.
PY - 2011
Y1 - 2011
N2 - To cite this article: Thomsen SF, Duffy DL, Kyvik KO, Skytthe A, Backer V. Risk of asthma in adult twins with type 2 diabetes and increased body mass index. Allergy 2010; DOI: 10.1111/j.1398-9995.2010.02504.x. ABSTRACT: Aim: To examine the relationship between asthma, type 2 diabetes and increased body mass index (BMI) in adult twins. Methods: We performed record linkage between questionnaire-defined asthma and BMI, and hospital discharge diagnoses of type 2 diabetes in 34 782 Danish twins, 20-71 years of age. Results: The risk of asthma was increased in subjects with type 2 diabetes relative to nondiabetic subjects both in men (13.5.5, P = 0.001 and in women (16.6.6, P = 0.001. The result remained significant after adjustment for age, BMI, smoking, symptoms of chronic bronchitis, marital status and zygosity, men: OR = 1.70 (1.07-2.70), P = 0.026; women: OR = 1.88 (1.24-2.85), P = 0.003. In this analysis, BMI remained a highly significant predictor for asthma independently of diabetes status in women, P
AB - To cite this article: Thomsen SF, Duffy DL, Kyvik KO, Skytthe A, Backer V. Risk of asthma in adult twins with type 2 diabetes and increased body mass index. Allergy 2010; DOI: 10.1111/j.1398-9995.2010.02504.x. ABSTRACT: Aim: To examine the relationship between asthma, type 2 diabetes and increased body mass index (BMI) in adult twins. Methods: We performed record linkage between questionnaire-defined asthma and BMI, and hospital discharge diagnoses of type 2 diabetes in 34 782 Danish twins, 20-71 years of age. Results: The risk of asthma was increased in subjects with type 2 diabetes relative to nondiabetic subjects both in men (13.5.5, P = 0.001 and in women (16.6.6, P = 0.001. The result remained significant after adjustment for age, BMI, smoking, symptoms of chronic bronchitis, marital status and zygosity, men: OR = 1.70 (1.07-2.70), P = 0.026; women: OR = 1.88 (1.24-2.85), P = 0.003. In this analysis, BMI remained a highly significant predictor for asthma independently of diabetes status in women, P
U2 - 10.1111/j.1398-9995.2010.02504.x
DO - 10.1111/j.1398-9995.2010.02504.x
M3 - Article
SN - 0105-4538
VL - 66
SP - 562
EP - 568
JO - Allergy
JF - Allergy
IS - 4
ER -