Response to pegylated interferon in a COVID-19-positive elderly woman with primary myelofibrosis treated with ruxolitinib

Arthur E Frankel; Renuka Reddy; Kayla R DeSuza; Khaled Deeb; Aaron F Carlin; Davey Smith; Yushuang Xie; Eknath Naik; Richard T Silver; Hans C Hasselbalch

doi:10.1002/ccr3.3997

Response to pegylated interferon in a COVID-19-positive elderly woman with primary myelofibrosis treated with ruxolitinib

Arthur E Frankel
, Renuka Reddy
, Kayla R DeSuza
, Khaled Deeb
, Aaron F Carlin
, Davey Smith
, Yushuang Xie
, Eknath Naik
, Richard T Silver
, Hans C Hasselbalch

Hæmatologisk Afdeling

Publikation: Bidrag til tidsskrift › Artikel › Forskning › peer review

Abstract

An 83-year-old female had asymptomatic SARS-CoV-2 infection while taking ruxolitinib. She remained RT-PCR positive for viral RNA for >120 days, and Pegylated interferon for 4 weeks led to viral RNA clearance. The observations support combination therapy of ruxolitinib + interferon for COVID-19.

Originalsprog	Engelsk
Sider (fra-til)	2228-2235
Antal sider	8
Tidsskrift	Clinical Case Reports
Vol/bind	9
Udgave nummer	4
DOI	https://doi.org/10.1002/ccr3.3997
Status	Udgivet - apr. 2021

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10.1002/ccr3.3997

Citationsformater

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title = "Response to pegylated interferon in a COVID-19-positive elderly woman with primary myelofibrosis treated with ruxolitinib",

abstract = "An 83-year-old female had asymptomatic SARS-CoV-2 infection while taking ruxolitinib. She remained RT-PCR positive for viral RNA for >120 days, and Pegylated interferon for 4 weeks led to viral RNA clearance. The observations support combination therapy of ruxolitinib + interferon for COVID-19.",

author = "Frankel, \{Arthur E\} and Renuka Reddy and DeSuza, \{Kayla R\} and Khaled Deeb and Carlin, \{Aaron F\} and Davey Smith and Yushuang Xie and Eknath Naik and Silver, \{Richard T\} and Hasselbalch, \{Hans C\}",

note = "{\textcopyright} 2021 The Authors. Clinical Case Reports published by John Wiley \& Sons Ltd.",

year = "2021",

month = apr,

doi = "10.1002/ccr3.3997",

language = "English",

volume = "9",

pages = "2228--2235",

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TY - JOUR

T1 - Response to pegylated interferon in a COVID-19-positive elderly woman with primary myelofibrosis treated with ruxolitinib

AU - Frankel, Arthur E

AU - Reddy, Renuka

AU - DeSuza, Kayla R

AU - Deeb, Khaled

AU - Carlin, Aaron F

AU - Smith, Davey

AU - Xie, Yushuang

AU - Naik, Eknath

AU - Silver, Richard T

AU - Hasselbalch, Hans C

PY - 2021/4

Y1 - 2021/4

N2 - An 83-year-old female had asymptomatic SARS-CoV-2 infection while taking ruxolitinib. She remained RT-PCR positive for viral RNA for >120 days, and Pegylated interferon for 4 weeks led to viral RNA clearance. The observations support combination therapy of ruxolitinib + interferon for COVID-19.

AB - An 83-year-old female had asymptomatic SARS-CoV-2 infection while taking ruxolitinib. She remained RT-PCR positive for viral RNA for >120 days, and Pegylated interferon for 4 weeks led to viral RNA clearance. The observations support combination therapy of ruxolitinib + interferon for COVID-19.

U2 - 10.1002/ccr3.3997

DO - 10.1002/ccr3.3997

M3 - Article

C2 - 33936671

SN - 2050-0904

VL - 9

SP - 2228

EP - 2235

JO - Clinical Case Reports

JF - Clinical Case Reports

IS - 4

ER -

Response to pegylated interferon in a COVID-19-positive elderly woman with primary myelofibrosis treated with ruxolitinib

Abstract

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