Reduced myo-inositol and total choline measured with cerebral MRS in acute thyrotoxic Graves' disease

T. V. Elberling, E. R. Danielsen, Å K. Rasmussen, U. Feldt-Rasmussen, G. Waldemar*, C. Thomsen

*Corresponding author af dette arbejde

    Publikation: Bidrag til tidsskriftArtikelForskningpeer review

    Abstract

    Neuropsychiatric symptoms in the acute thyrotoxic phase of Graves' disease suggest involvement of brain processes. Short-echo-time proton MRS was used to measure the cerebral metabolite profile in newly diagnosed and untreated Graves' disease. Sixteen patients with Graves' disease and 18 age- and sex-matched healthy volunteers were studied. The patients had significantly reduced total choline and myo-inositol in the acute phase of Graves' thyrotoxicosis compared with the healthy volunteers.

    OriginalsprogEngelsk
    Sider (fra-til)142-145
    Antal sider4
    TidsskriftNeurology
    Vol/bind60
    Udgave nummer1
    DOI
    StatusUdgivet - 14 jan. 2003

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