Quantification of portal venous blood flow during fasting and after a standardized meal - a MRI phase-mapping study

C. Thomsen, F. Ståhlberg, O. Henriksen

    Publikation: Bidrag til tidsskriftArtikelForskningpeer review

    Abstrakt

    Portal venous blood flow was measured with a double-oblique phase-sensitive magnetic resonance imaging (MRI) flow measurement technique in six healthy volunteers after 7 h of fasting. A standard liquid meal with an energy content of 4200 kJ, containing equal parts of carbohydrate, protein and fat was given to the volunteers while in the scanner. Flow measurements were performed 5, 15 and 30 min after intake of the meal. The average portal vein blood flow was 0.88 ± 0.17 l · min-1 during fasting. After intake of the standard meal, flow increased by 30,67 and 111% after 5, 15 and 30 min, respectively. This study shows that a non-invasive MRI technique can be used for volume flow determinations in the portal vein and that physiological changes in flow can be quantified. The technique may be of clinical value in evaluation of patients with abdominal angina as well as patients with portal hypertension.

    OriginalsprogEngelsk
    Sider (fra-til)242-247
    Antal sider6
    TidsskriftEuropean Radiology
    Vol/bind3
    Udgave nummer3
    DOI
    StatusUdgivet - 1 maj 1993

    Fingeraftryk Udforsk hvilke forskningsemner 'Quantification of portal venous blood flow during fasting and after a standardized meal - a MRI phase-mapping study' indeholder.

    Citationsformater