Primary peritoneal carcinoma: A rare neoplasm with pleomorphic trophoblastic morphology. Case report

Charlotte Winther Madsen, Jane Preuss Hasselby*, Lise Grupe Larsen

*Corresponding author af dette arbejde

    Publikation: Bidrag til tidsskriftArtikelForskningpeer review

    Abstract

    We report a case of primary peritoneal carcinoma with trophoblastic morphology in a 78-year-old woman, diagnosed by histological and immunohistochemical analysis of surgically resected specimens, including the omentum and part of the small bowel. Microscopically, the resected specimens showed diffuse infiltration of a poorly differentiated tumor. Numerous large, often multinucleated cells were seen, and mitotic figures were frequent. Immunohistochemical staining showed a positive reaction for most cytokeratins, EP4, EMA, CA-125, Glut1, WT1, β-hCG and PLAP. We reached a diagnosis of primary peritoneal carcinoma with trophoblastic morphology. To our knowledge this morphology of a primary peritoneal carcinoma has not been described previously.

    OriginalsprogEngelsk
    Sider (fra-til)574-579
    Antal sider6
    TidsskriftAPMIS
    Vol/bind114
    Udgave nummer7-8
    DOI
    StatusUdgivet - jul. 2006

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