TY - JOUR
T1 - Preventing poor vocational functioning in psychosis through early intervention
AU - Ten Velden Hegelstad, Wenche
AU - Bronnick, Kolbjorn S.
AU - Barder, Helene Eidsmo
AU - Evensen, Julie Horgen
AU - Haahr, Ulrik
AU - Joa, Inge
AU - Johannessen, Jan Olav
AU - Langeveld, Johannes
AU - Larsen, Tor Ketil
AU - Melle, Ingrid
AU - Opjordsmoen, Stein
AU - Rund, Bjørn Rishovd
AU - Rossberg, Jan Ivar
AU - Simonsen, Erik
AU - Vaglum, Per Wiggen
AU - McGlashan, Thomas H.
AU - Friis, Svein
PY - 2017/1/1
Y1 - 2017/1/1
N2 - Objective: This study tested the hypothesis that early detection of psychosis improves long-term vocational functioning through the prevention of negative symptom development. Methods: Generalized estimating equations and mediation analysis were conducted to examine the association between employment and negative symptoms over ten years among patients in geographic areas characterized by usual detection (N=140) or early detection (N=141) of psychosis. Results: Improved vocational outcome after ten years among patients in the early-detection area was mediated by lower levels of negative symptoms during the first five years. Regardless of symptoms, rates of full-time employment or study were lower among patients in the usual-detection versus the early-detection area. Conclusions: Patients from an early-detection area attained lower negative symptom levels earlier compared with patients from a usual-detection area, which seemed to have facilitated vocational careers.
AB - Objective: This study tested the hypothesis that early detection of psychosis improves long-term vocational functioning through the prevention of negative symptom development. Methods: Generalized estimating equations and mediation analysis were conducted to examine the association between employment and negative symptoms over ten years among patients in geographic areas characterized by usual detection (N=140) or early detection (N=141) of psychosis. Results: Improved vocational outcome after ten years among patients in the early-detection area was mediated by lower levels of negative symptoms during the first five years. Regardless of symptoms, rates of full-time employment or study were lower among patients in the usual-detection versus the early-detection area. Conclusions: Patients from an early-detection area attained lower negative symptom levels earlier compared with patients from a usual-detection area, which seemed to have facilitated vocational careers.
UR - http://www.scopus.com/inward/record.url?scp=85008147869&partnerID=8YFLogxK
U2 - 10.1176/appi.ps.201500451
DO - 10.1176/appi.ps.201500451
M3 - Letter
C2 - 27582238
AN - SCOPUS:85008147869
SN - 1075-2730
VL - 68
SP - 100
EP - 103
JO - Psychiatric Services
JF - Psychiatric Services
IS - 1
ER -