Predicting the risk of a false-positive test for women following a mammography screening programme

Sisse Helle Njor, Anne Helene Olsen, Walter Schwartz, Ilse Vejborg, Elsebeth Lynge

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    Abstrakt

    Objectives: The objectives of this study was to provide a simple estimate of the cumulative risk of a false-positive test for women participating in mammography screening. To test the method, we used data from two well-established, organized mammography screening programmes offering biennial screening to women aged 50-69 years in Copenhagen and Fyn, Denmark. Methods: We defined the outcome from a screen as being either a false-positive test or not a falsepositive test. We then tested whether the outcomes from subsequent screens were independent, and afterwards estimated the risk over 10 screens of a false-positive test, i.e. the risk of getting at least one false-positive test for a woman participating in all 10 screens typically offered in Europe. Results: The outcomes of subsequent screens were found to be independent. After completion of screening rounds 3-5, the risk of a false-positive test over 10 screens was predicted to be 15.8-21.5% for a woman participating in the programme in Copenhagen, and 8.1-9.6% for a woman participating in the programme in Fyn. Conclusions: Our study showed that a relatively robust prediction of the risk of a false-positive test over 10 screens can be calculated in a simple way relatively early after the start of a mammography screening programme.

    OriginalsprogEngelsk
    Sider (fra-til)94-97
    Antal sider4
    TidsskriftJournal of Medical Screening
    Vol/bind14
    Udgave nummer2
    DOI
    StatusUdgivet - 1 jun. 2007

    Fingeraftryk Udforsk hvilke forskningsemner 'Predicting the risk of a false-positive test for women following a mammography screening programme' indeholder.

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