Platelet survival, platelet factor-4 and bleeding time in myeloproliferative disorders

Dag Berild, Hans Hasselbalch, Jens Bjerre Knudsen

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    Abstrakt

    In 27 patients with myloproliferative disorders observations on thrombohaemorrhagic complications, platelet function tests and spleen size were made. Sixteen patients had thrombotic or haemorrhagic episodes. All 27 patients had elevated platelet factor-4 and 25 patients had a shortened platelet survival. Patients with myelofibrosis had a significantly shorter platelet survival than patients with polycythaemia vera (p<0.05). Seven out of 23 patients investigated had prolonged bleeding time. The observed abnormalities of platelet function tests were not related to thrombohaemorrhagic complications or spleen size.

    OriginalsprogEngelsk
    Sider (fra-til)497-501
    Antal sider5
    TidsskriftScandinavian Journal of Clinical and Laboratory Investigation
    Vol/bind47
    Udgave nummer5
    DOI
    StatusUdgivet - 1 jan. 1987

    Fingeraftryk Udforsk hvilke forskningsemner 'Platelet survival, platelet factor-4 and bleeding time in myeloproliferative disorders' indeholder.

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