Pediatric toxic epidermal necrolysis treated successfully with infliximab

Lana Chafranska, Ditte M Saunte, Nille Behrendt, Ulrikka Nygaard, Ryan J Christensen, Carsten Sand, Gregor B Jemec

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Abstrakt

Successful management of toxic epidermal necrolysis (TEN) with tumor necrosis factor-α inhibitors has been described in adults. We present a case of a 7-year-old boy with infection-associated TEN, diagnosed by typical clinical and histopathological features, most likely caused by Mycoplasma pneumoniae. Treatment with a single dose of infliximab 5 mg/kg intravenously on day 5 after the onset of symptoms was followed by cessation of all blister formation over 3 days and complete resolution within a week. Sequelae were mild, consisting of postinflammatory hyperpigmentation and dry eyes.

OriginalsprogEngelsk
Sider (fra-til)342-345
Antal sider4
TidsskriftPediatric Dermatology
Vol/bind36
Udgave nummer3
DOI
StatusUdgivet - maj 2019

Bibliografisk note

� 2019 Wiley Periodicals, Inc.

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