Osteoporosis and vertebral fractures in men aged 60-74 years

Morten Frost, Kristian Wraae, Bo Abrahamsen, Mikkel Høiberg, Claus Hagen, Marianne Andersen, Kim Brixen

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    Background: limited information on the prevalence of osteoporosis and VFxs in men in high-risk populations is available. The choice of reference values for dual X-ray absorptiometry (DXA) is debated. We evaluated the prevalence of osteoporosis and vertebral deformities in a population-based sample of men. Methods: bone mineral density (BMD) was measured and vertebral deformities assessed using DXA and VFx assessment (VFA), respectively, in a random sample of 600 Danish men aged 60-74 years. Osteoporosis was defined as a T-score of -2.5 or less. Results: the study population was comparable with the background population with regard to age, body mass index and comorbidity. Osteoporosis was diagnosed in less than 1% of the participants at inclusion. Using Danish and NHANES III reference data, 10.2 and 11.5% of the study population had osteoporosis, respectively. In all, 6.3% participants had at least one VFx. BMD was significantly lower in participants with vertebral deformities, but only 24% of these cases had osteoporosis. Conclusions: osteoporosis and VFxs are prevalent in men aged 60-74 years. Although the majority of deformities were present in individuals without osteoporosis, BMD was lower in patients with VFxs at all sites investigated. Male osteoporosis was markedly underdiagnosed.

    Sider (fra-til)171-177
    Antal sider7
    TidsskriftAge and Ageing
    Udgave nummer2
    StatusUdgivet - 1 mar. 2012


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