Osteoporosis and vertebral fractures in men aged 60-74 years

Morten Frost, Kristian Wraae, Bo Abrahamsen, Mikkel Høiberg, Claus Hagen, Marianne Andersen, Kim Brixen

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    Abstrakt

    Background: limited information on the prevalence of osteoporosis and VFxs in men in high-risk populations is available. The choice of reference values for dual X-ray absorptiometry (DXA) is debated. We evaluated the prevalence of osteoporosis and vertebral deformities in a population-based sample of men. Methods: bone mineral density (BMD) was measured and vertebral deformities assessed using DXA and VFx assessment (VFA), respectively, in a random sample of 600 Danish men aged 60-74 years. Osteoporosis was defined as a T-score of -2.5 or less. Results: the study population was comparable with the background population with regard to age, body mass index and comorbidity. Osteoporosis was diagnosed in less than 1% of the participants at inclusion. Using Danish and NHANES III reference data, 10.2 and 11.5% of the study population had osteoporosis, respectively. In all, 6.3% participants had at least one VFx. BMD was significantly lower in participants with vertebral deformities, but only 24% of these cases had osteoporosis. Conclusions: osteoporosis and VFxs are prevalent in men aged 60-74 years. Although the majority of deformities were present in individuals without osteoporosis, BMD was lower in patients with VFxs at all sites investigated. Male osteoporosis was markedly underdiagnosed.

    OriginalsprogEngelsk
    Artikelnummerafr170
    Sider (fra-til)171-177
    Antal sider7
    TidsskriftAge and Ageing
    Vol/bind41
    Udgave nummer2
    DOI
    StatusUdgivet - 1 mar. 2012

    Fingeraftryk

    Udforsk hvilke forskningsemner 'Osteoporosis and vertebral fractures in men aged 60-74 years' indeholder.

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