Orientia tsutsugamushi påvist ved mikrobiomdiagnostik

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Scrub typhus is caused by the mite-borne bacterium Orientia tsutsugamushi. Imported cases have been suspected in Denmark but no diagnostic method has yet been available to confirm the diagnosis. This is a case report of a 38-year-old male admitted to hospital with high fever, severe malaise and headache after returning from Malaysia. Scrub typhus was suspected and the patient recovered after one week of doxycycline treatment. The pathogen was identified by use of microbiome 16S/18S rRNA next-generation sequencing on ethylenediamine tetraacetic acid (EDTA) blood, which in the future may serve an important role in the investigation of travel-associated infections.

Bidragets oversatte titelOrientia tsutsugamushi detected by microbiome diagnostics
Antal sider4
TidsskriftUgeskrift for Laeger
Udgave nummer40
StatusUdgivet - 2 okt. 2023

Bibliografisk note

Published under Open Access CC-BY-NC-BD 4.0. https://creativecommons.org/licenses/by-nc-nd/4.0/.


  • Adult
  • Doxycycline/therapeutic use
  • Humans
  • Male
  • Orientia tsutsugamushi/genetics
  • RNA, Ribosomal, 16S
  • Scrub Typhus/complications
  • Travel
  • Travel-Related Illness


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