Optiknee 2022: consensus recommendations to optimise knee health after traumatic knee injury to prevent osteoarthritis

Jackie L Whittaker*, Adam G Culvenor, Carsten Bogh Juhl, Bjørnar Berg, Alessio Bricca, Stephanie Rose Filbay, Pætur Holm, Erin Macri, Anouk P Urhausen, Clare L Ardern, Andrea M Bruder, Garrett S Bullock, Allison M Ezzat, Michael Girdwood, Melissa Haberfield, Mick Hughes, Lina Holm Ingelsrud, Karim M Khan, Christina Y Le, Justin M LoscialeMatilde Lundberg, Maxi Miciak, Britt Elin Øiestad, Brooke Patterson, Anu M Räisänen, Søren T Skou, Jonas Bloch Thorlund, Clodagh Toomey, Linda K Truong, Belle L van Meer, Thomas James West, James Justin Young, L Stefan Lohmander, Carolyn Emery, May Arna Risberg, Marienke van Middelkoop, Ewa M. Roos, Kay M Crossley

*Corresponding author af dette arbejde

Publikation: Bidrag til tidsskriftArtikelForskningpeer review


The goal of the OPTIKNEE consensus is to improve knee and overall health, to prevent osteoarthritis (OA) after a traumatic knee injury. The consensus followed a seven-step hybrid process. Expert groups conducted 7 systematic reviews to synthesise the current evidence and inform recommendations on the burden of knee injuries; risk factors for post-traumatic knee OA; rehabilitation to prevent post-traumatic knee OA; and patient-reported outcomes, muscle function and functional performance tests to monitor people at risk of post-traumatic knee OA. Draft consensus definitions, and clinical and research recommendations were generated, iteratively refined, and discussed at 6, tri-weekly, 2-hour videoconferencing meetings. After each meeting, items were finalised before the expert group (n=36) rated the level of appropriateness for each using a 9-point Likert scale, and recorded dissenting viewpoints through an anonymous online survey. Seven definitions, and 8 clinical recommendations (who to target, what to target and when, rehabilitation approach and interventions, what outcomes to monitor and how) and 6 research recommendations (research priorities, study design considerations, what outcomes to monitor and how) were voted on. All definitions and recommendations were rated appropriate (median appropriateness scores of 7-9) except for two subcomponents of one clinical recommendation, which were rated uncertain (median appropriateness score of 4.5-5.5). Varying levels of evidence supported each recommendation. Clinicians, patients, researchers and other stakeholders may use the definitions and recommendations to advocate for, guide, develop, test and implement person-centred evidence-based rehabilitation programmes following traumatic knee injury, and facilitate data synthesis to reduce the burden of knee post-traumatic knee OA.

Sider (fra-til)1393-1405
Antal sider13
TidsskriftBritish journal of sports medicine
Udgave nummer24
Tidlig onlinedato15 nov. 2022
StatusUdgivet - dec. 2022

Bibliografisk note

© Author(s) (or their employer(s)) 2022. No commercial re-use. See rights and permissions. Published by BMJ.


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  • OPTIKNEE Consensus

    Whittaker, J. L., Holm, P. M., Culvenor, A. G., Roos, E. M., Crossley, K. M. & Juhl, C. B.


    Projekter: ProjektForskning