Opioider mod refraktær dyspnø i palliativ fase

Birgit Aabom; Elisabeth Bendstrup; Per Sjøgren; Anders Løkke; Burhan Shaker; Torgny Wilcke; Bodil Abild Jespersen; Ole Hilberg; Kristoffer Marsaa

Opioider mod refraktær dyspnø i palliativ fase

Birgit Aabom, Elisabeth Bendstrup, Per Sjøgren, Anders Løkke, Burhan Shaker, Torgny Wilcke, Bodil Abild Jespersen, Ole Hilberg, Kristoffer Marsaa

Klinisk Onkologisk Afdeling

Publikation: Bidrag til tidsskrift › Review › Forskning › peer review

Abstract

Dyspnoea is cardinal symptom in chronic obstructive lung disease and common in palliative phases of cancer and other chronic medical diseases. Low-dose opioids is frequently used off-label. This review examines the evidence and safety as well as administration forms and pharmacokinetics using low dose opioids for dyspnoea. Conclusively, there seems to be clinical efficacy although further studies are needed. Furthermore, the authors recommend Danish Medical Agency to legislate low-dose morphine to palliative patients with refractory dyspnoea.

Bidragets oversatte titel	Opioids for refractory dyspnoea in palliation
Originalsprog	Dansk
Artikelnummer	V04200225
Antal sider	9
Tidsskrift	Ugeskrift for laeger
Vol/bind	182
Udgave nummer	40
Status	Udgivet - 28 sep. 2020

Adgang til dokumentet

https://ugeskriftet.dk/videnskab/opioider-mod-refraktaer-dyspno-i-palliativ-fase

Citationsformater

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AU - Aabom, Birgit

AU - Bendstrup, Elisabeth

AU - Sjøgren, Per

AU - Løkke, Anders

AU - Shaker, Burhan

AU - Wilcke, Torgny

AU - Jespersen, Bodil Abild

AU - Hilberg, Ole

AU - Marsaa, Kristoffer

PY - 2020/9/28

Y1 - 2020/9/28

N2 - Dyspnoea is cardinal symptom in chronic obstructive lung disease and common in palliative phases of cancer and other chronic medical diseases. Low-dose opioids is frequently used off-label. This review examines the evidence and safety as well as administration forms and pharmacokinetics using low dose opioids for dyspnoea. Conclusively, there seems to be clinical efficacy although further studies are needed. Furthermore, the authors recommend Danish Medical Agency to legislate low-dose morphine to palliative patients with refractory dyspnoea.

AB - Dyspnoea is cardinal symptom in chronic obstructive lung disease and common in palliative phases of cancer and other chronic medical diseases. Low-dose opioids is frequently used off-label. This review examines the evidence and safety as well as administration forms and pharmacokinetics using low dose opioids for dyspnoea. Conclusively, there seems to be clinical efficacy although further studies are needed. Furthermore, the authors recommend Danish Medical Agency to legislate low-dose morphine to palliative patients with refractory dyspnoea.

M3 - Review

C2 - 33000737

SN - 0041-5782

VL - 182

JO - Ugeskrift for laeger

JF - Ugeskrift for laeger

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ER -

Opioider mod refraktær dyspnø i palliativ fase

Abstract

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Citationsformater