NSAID og stentanlæggelse ved akut kolorektal cancer

Xenia Lea Schefte, Malene Broholm Andersen, Ismail Gögenur

Publikation: Bidrag til tidsskriftReviewForskningpeer review

Abstract

Surgical stress response includes an inflammatory response with production of enzymes which promote tumour progression and potentially alter tumour microenvironment in colorectal cancer patients. SEMS placement as a "bridge-to-surgery" approach was introduced alternatively to acute resection to improve short-term outcomes and mortality. However, SEMS may lead to inflammation with potential long-term oncological complications. The anti-inflammatory effect of NSAID is used in gastrointestinal procedures to elude inflammatory complications. This review summarises the current knowledge in this field and asks whether this could be transferred to other GI procedures e.g. self-expandable metal stent placement.

Bidragets oversatte titelNSAID and stent placement in acute colorectal cancer
OriginalsprogDansk
ArtikelnummerV03220229
Sider (fra-til)1066-1068
Antal sider3
TidsskriftUgeskrift for laeger
Vol/bind185
Udgave nummer11
Tidlig onlinedato30 jan. 2023
StatusUdgivet - 29 maj 2023

Emneord

  • Humans
  • Treatment Outcome
  • Anti-Inflammatory Agents, Non-Steroidal/therapeutic use
  • Intestinal Obstruction/etiology
  • Self Expandable Metallic Stents/adverse effects
  • Colorectal Neoplasms/surgery
  • Retrospective Studies
  • Stents/adverse effects
  • Tumor Microenvironment

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