Nosocomial pneumonia in an intensive care unit in a danish university hospital: Incidence, mortality and etiology

Søren Loumann Nielsen, Bent Røder, Pascal Magnussen, Allan Engquist, Niels Frimodt-Møller

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    Abstrakt

    We studied the patients admitted to the ICU at a Danish university hospital during 1 year with respect to nosocomial pneumonia (NP). Among 242 patients, who stayed more than 48 h, 23 (10% developed NP. Patients with NP had significantly higher mortality (43% vs. 19% p < 0.05), longer median stay (276 h vs. 99 h, p < 0.05) and a longer median intubation period (256 h vs. 74 h, p < 0.05). In the NP group surgical patients were overrepresented as compared to medical patients (74% vs. 45% p < 0.05). Thoracotomy, treatment with H-2 blockers and immunosuppression represented significant risk factors. Considering the etiology, Enterobacteriaceae and Pseudomonas aeruginosa constituted 43% of the cases in strong contrast to the low frequency of these pathogens in community-acquired pneumonia. NP in the ICU patient is a resource consuming disease associated with a high mortality (43% which is related to the frequent severe underlying diseases of these patients.

    OriginalsprogEngelsk
    Sider (fra-til)65-70
    Antal sider6
    TidsskriftScandinavian Journal of Infectious Diseases
    Vol/bind24
    Udgave nummer1
    DOI
    StatusUdgivet - 1 jan. 1992

    Fingeraftryk Udforsk hvilke forskningsemner 'Nosocomial pneumonia in an intensive care unit in a danish university hospital: Incidence, mortality and etiology' indeholder.

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