Noninvasive detection of focal seizures in ambulatory patients

Philippe Ryvlin, Leila Cammoun, Ilona Hubbard, France Ravey, Sandor Beniczky, David Atienza

Publikation: Bidrag til tidsskriftReviewForskningpeer review


Reliably detecting focal seizures without secondary generalization during daily life activities, chronically, using convenient portable or wearable devices, would offer patients with active epilepsy a number of potential benefits, such as providing more reliable seizure count to optimize treatment and seizure forecasting, and triggering alarms to promote safeguarding interventions. However, no generic solution is currently available to reach these objectives. A number of biosignals are sensitive to specific forms of focal seizures, in particular heart rate and its variability for seizures affecting the neurovegetative system, and accelerometry for those responsible for prominent motor activity. However, most studies demonstrate high rates of false detection or poor sensitivity, with only a minority of patients benefiting from acceptable levels of accuracy. To tackle this challenging issue, several lines of technological progress are envisioned, including multimodal biosensing with cross-modal analytics, a combination of embedded and distributed self-aware machine learning, and ultra-low-power design to enable appropriate autonomy of such sophisticated portable solutions.

Sider (fra-til)S47-S54
Vol/bind61 Suppl 1
Tidlig onlinedato2 jun. 2020
StatusUdgivet - nov. 2020

Bibliografisk note

© 2020 The Authors. Epilepsia published by Wiley Periodicals LLC on behalf of International League Against Epilepsy.


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