Non‐Hodgkin malignant lymphomas and Hodgkin's disease in first‐degree relatives: Evidence for a mutual genetic predisposition?

The occurrence of malignant lymphomas in 3 siblings is described. The cases include the first report of Hodgkin's disease and non‐Hodgkin malignant lymphoma in dizygotic twins. Another remarkable feature was the development of malignant lymphoma, when the siblings were at the same age. Although a transmissible agent or environmental factors cannot be excluded in this family, our observations may suggest a mutual genetic predisposition in Hodgkin's disease and non‐Hodgkin malignant lymphoma.