Neonatal Anthropometrics and Obesity Treatment Response in Children and Adolescents

Ulrik Lausten-Thomsen*, Morten Asp Vonsild Lund, Sara Elizabeth Stinson, Christine Frithioff-Bøjsøe, Louise Aas Holm, Jennifer Lyn Baker, Cilius Esmann Fonvig, Michael Christiansen, Lars Ängquist, Torben Hansen, Jens-Christian Holm

*Corresponding author af dette arbejde

Publikation: Bidrag til tidsskriftArtikelForskningpeer review

Abstrakt

OBJECTIVE: To investigate the relationship between in utero growth conditions, as indicated by neonatal anthropometric measures, and childhood obesity treatment response, to examine the potential usefulness of neonatal anthropometrics as a potential childhood obesity treatment stratification tool.

STUDY DESIGN: The study included 2474 children and adolescents with obesity (mean age, 11.2 years; range, 5.0-18.9 years) treated at the Children's Obesity Clinic in Holbæk, Denmark. Treatment response was registered prospectively, and neonatal data were collected from national electronic registers.

RESULTS: Birth weight, birth length, birth weight for gestational age, and large for gestational age status were positively associated with the degree of obesity at treatment initiation. After a mean (SD) of 1.27 (0.69) years of enrollment in obesity treatment, the children exhibited a mean reduction of -0.32 (0.50) in body mass index SD score. No significant associations between neonatal anthropometric measures and childhood obesity treatment response were detected.

CONCLUSIONS: Neonatal anthropometric measures were positively associated with the degree of obesity at treatment initiation but not with response to multidisciplinary treatment of childhood obesity. Individualization of obesity treatment based on neonatal anthropometry does not seem warranted.

OriginalsprogEngelsk
TidsskriftJournal of Pediatrics
DOI
StatusUdgivet, E-publikation før trykning - 11 nov. 2021

Bibliografisk note

Copyright © 2021 The Author(s). Published by Elsevier Inc. All rights reserved.

Fingeraftryk

Udforsk hvilke forskningsemner 'Neonatal Anthropometrics and Obesity Treatment Response in Children and Adolescents' indeholder.

Citationsformater