TY - JOUR
T1 - Multimodality Imaging in Cranial Giant Cell Arteritis
T2 - First Experience with High-Resolution T1-Weighted 3D Black Blood without Contrast Enhancement Magnetic Resonance Imaging
AU - Brittain, Jane Maestri
AU - Hansen, Michael Stormly
AU - Carlsen, Jonathan Frederik
AU - Brandt, Andreas Hjelm
AU - Terslev, Lene
AU - Jensen, Mads Radmer
AU - Lindberg, Ulrich
AU - Larsson, Henrik Bo Wiberg
AU - Heegaard, Steffen
AU - Døhn, Uffe Møller
AU - Klefter, Oliver Niels
AU - Wiencke, Anne Katrine
AU - Subhi, Yousif
AU - Hamann, Steffen
AU - Haddock, Bryan
PY - 2023/12/29
Y1 - 2023/12/29
N2 - In order to support or refute the clinical suspicion of cranial giant cell arteritis (GCA), a supplemental imaging modality is often required. High-resolution black blood Magnetic Resonance Imaging (BB MRI) techniques with contrast enhancement can visualize artery wall inflammation in GCA. We compared findings on BB MRI without contrast enhancement with findings on 2-deoxy-2-[18F]fluoro-D-glucose positron emission tomography/low-dose computed tomography (2-[18F]FDG PET/CT) in ten patients suspected of having GCA and in five control subjects who had a 2-[18F]FDG PET/CT performed as a routine control for malignant melanoma. BB MRI was consistent with 2-[18F]FDG PET/CT in 10 out of 10 cases in the group with suspected GCA. In four out of five cases in the control group, the BB MRI was consistent with 2-[18F]FDG PET/CT. In this small population, BB MRI without contrast enhancement shows promising performance in the diagnosis of GCA, and might be an applicable imaging modality in patients.
AB - In order to support or refute the clinical suspicion of cranial giant cell arteritis (GCA), a supplemental imaging modality is often required. High-resolution black blood Magnetic Resonance Imaging (BB MRI) techniques with contrast enhancement can visualize artery wall inflammation in GCA. We compared findings on BB MRI without contrast enhancement with findings on 2-deoxy-2-[18F]fluoro-D-glucose positron emission tomography/low-dose computed tomography (2-[18F]FDG PET/CT) in ten patients suspected of having GCA and in five control subjects who had a 2-[18F]FDG PET/CT performed as a routine control for malignant melanoma. BB MRI was consistent with 2-[18F]FDG PET/CT in 10 out of 10 cases in the group with suspected GCA. In four out of five cases in the control group, the BB MRI was consistent with 2-[18F]FDG PET/CT. In this small population, BB MRI without contrast enhancement shows promising performance in the diagnosis of GCA, and might be an applicable imaging modality in patients.
U2 - 10.3390/diagnostics14010081
DO - 10.3390/diagnostics14010081
M3 - Article
C2 - 38201390
SN - 2075-4418
VL - 14
JO - Diagnostics
JF - Diagnostics
IS - 1
ER -