Mitral and aortic valvular flow: Quantification with MR phase mapping

Lars Sondergaard*, Carsten Thomsen, Freddy Stahlberg, Erik Gymoese, Knud Lindvig, Per Hildebrandt, Ole Henriksen

*Corresponding author af dette arbejde

    Publikation: Bidrag til tidsskriftArtikelForskningpeer review


    When magnetic resonance phase mapping is used to quantitate valvular blood flow, the presence of higher‐order‐motion terms may cause a loss of phase information. To overcome this problem, a sequence with reduced encoding for higher‐order motion was used, achieved by decreasing the duration of the flow‐encoding gradient to 2.2 msec. Tested on a flow phantom simulating a severe valvular stenosis, the sequence was found to be robust for higher‐order motion within the clinical velocity range. In eight healthy volunteers, mitral and aortic volume flow rates and peak velocities were quantified by means of phase mapping and compared with results of the indicator‐dilution technique and Dop‐pler echocardiography, respectively. Statistically significant correlations were found between phase mapping and the other two techniques. Similar studies in patients with valvular disease indicate that phase mapping is also valid for pathologic conditions. Phase mapping may be used as a noninva‐sive clinical tool for flow quantification in heart valve disease.

    Sider (fra-til)295-302
    Antal sider8
    TidsskriftJournal of Magnetic Resonance Imaging
    Udgave nummer3
    StatusUdgivet - 1 jan. 1992


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