Metformin og obstetriske patienter

Katrine Dahl Pedersen, Nathalie Søderhamn Bülow, Kasper Aaboe, Julie Galsgaard, Helle Sand Odgaard, Elisabeth Reinhardt Mathiesen, Jeannet Lauenborg

    Publikation: Bidrag til tidsskriftReviewForskningpeer review


    Polycystic ovary syndrome (PCOS) is associated with insulin resistance, infertility, obesity and gestational complications. Metformin is widely used in fertility treatment of women with PCOS, due to a suggested positive effect of continued metformin treatment beyond the first trimester on pregnancy complications. Larger randomized trials have failed to confirm this. Metformin treatment has not been found to be superior to insulin treatment in women with gestational diabetes and may be associated with long-term consequences in the children in the form of overweight and disturbed glucose metabolism.

    Bidragets oversatte titelMetformin and the obstetric patient
    Sider (fra-til)1420-1423
    Antal sider4
    TidsskriftUgeskrift for laeger
    Udgave nummer15
    Tidlig onlinedato7 dec. 2015
    StatusUdgivet - 25 jul. 2016


    • Breast Feeding
    • Diabetes, Gestational/drug therapy
    • Female
    • Humans
    • Hypoglycemic Agents/adverse effects
    • Metformin/adverse effects
    • Polycystic Ovary Syndrome/drug therapy
    • Pregnancy
    • Pregnancy Trimester, Second
    • Pregnancy Trimester, Third
    • Prenatal Exposure Delayed Effects


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