Metaboliske forstyrrelser ved behandling af maligne haematologiske sygdomme--det akutte tumorlysesyndrom.

S. H. Nielsen, H. C. Hasselbalch, H. S. Birgens

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    Abstrakt

    The acute tumor-lysis syndrome is a potentially fatal complication which characteristically arises during initial chemotherapy of malignant hematological diseases with large tumor burdens. The syndrome is characterized by hyperphosphatemia, hypocalcemia, hyperuricemia and often acute renal failure. Prior to chemotherapy the patient should be treated for 12-24 hour with intensified diuresis to ensure optimal renal function. The treatment of the fully developed syndrome is hemodialysis. Three cases of TLS which developed during initial chemotherapy of patients with acute lymnphoblastic leukemia and non-Hodgkin lymphoma are presented.

    Bidragets oversatte titelMetabolic disorders in the treatment of malignant hematologic diseases--the acute tumor lysis syndrome
    OriginalsprogDansk
    Sider (fra-til)2952-2953
    Antal sider2
    TidsskriftUgeskrift for laeger
    Vol/bind153
    Udgave nummer42
    StatusUdgivet - 14 okt. 1991

    Fingeraftryk Udforsk hvilke forskningsemner 'Metaboliske forstyrrelser ved behandling af maligne haematologiske sygdomme--det akutte tumorlysesyndrom.' indeholder.

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