Medikamentel behandling af kemoterapiinduceret kvalme og opkastning

Jørn Herrstedt*

*Corresponding author af dette arbejde

    Publikation: Bidrag til tidsskriftArtikelForskningpeer review

    Abstract

    Patients consider nausea and vomiting among the worst side effects of chemotherapy. This paper reviews the development of antiemetics during the past 12 years, focusing on the neurokinin (NK)1 -receptor antagonist, aprepitant, and the new 5-HT3 -receptor antagonist palonosetron. Evidence-based recommendations for prophylaxis of chemotherapy-induced nausea and vomiting are given. Antiemetics are effective in prevention of vomiting, but less effective against nausea. Therefore studies with potential new antiemetics, such as olanzapine and ghrelin are awaited with suspense.

    Bidragets oversatte titelMedical treatment of chemotherapy-induced nausea and vomiting
    OriginalsprogDansk
    Sider (fra-til)799-805
    Antal sider7
    TidsskriftUgeskrift for laeger
    Vol/bind169
    Udgave nummer9
    StatusUdgivet - 26 feb. 2007

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